Development and validation of a prediction score for safe outpatient colorectal resections.
Détails
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Accès restreint UNIL
Etat: Public
Version: Final published version
Licence: Non spécifiée
Accès restreint UNIL
Etat: Public
Version: Final published version
Licence: Non spécifiée
ID Serval
serval:BIB_27AFB3FF663E
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Titre
Development and validation of a prediction score for safe outpatient colorectal resections.
Périodique
Surgery
ISSN
1532-7361 (Electronic)
ISSN-L
0039-6060
Statut éditorial
Publié
Date de publication
02/2022
Peer-reviewed
Oui
Volume
171
Numéro
2
Pages
336-341
Langue
anglais
Notes
Publication types: Journal Article ; Validation Study
Publication Status: ppublish
Publication Status: ppublish
Résumé
Avoiding unnecessary inpatient stay may decrease hospital-acquired complications and costs while increasing patient satisfaction. This study aimed to develop and validate a score to identify patients eligible for safe same-day discharge after colorectal resections.
This bi-institutional retrospective cohort study included consecutive patients undergoing elective colon and rectal resections (2011-2018) for benign and malignant indications. Two multivariable logistic models were developed based on demographic and surgical risk factors to predict a combined endpoint (ileus, anastomotic leak, intra-abdominal abscess, and readmission). Development and validation datasets were randomly sampled from the entire cohort. Areas under the receiver operating characteristic curves (AUC) were evaluated, and Hosmer-Lemeshow goodness-of-fit tests were used to assess validation model fit.
Of 5,389 patients, 1,182 (21.9%) experienced at least one complication of the combined endpoint. Male gender, open surgery, ASA ≥3, wound class ≥3, ileostomy, surgical duration >3 hours, and perioperative IV fluids >3 L all had significantly greater odds of the combined endpoint in the parsimonious multivariable model (all P < .05). The reduced model considering only the 4 variables with the highest OR (>1.5) contained open surgery, ASA ≥3, wound class ≥3, and surgical duration ≥3 hours as predictors (all P < .05, AUC of 0.65; 95% CI 0.63, 0.68). Both the parsimonious model and the reduced model demonstrated no lack of fit in the validation cohort.
The suggested score composed of preand intraoperative items may help physicians decide on patients' same-day discharge after colorectal resection.
This bi-institutional retrospective cohort study included consecutive patients undergoing elective colon and rectal resections (2011-2018) for benign and malignant indications. Two multivariable logistic models were developed based on demographic and surgical risk factors to predict a combined endpoint (ileus, anastomotic leak, intra-abdominal abscess, and readmission). Development and validation datasets were randomly sampled from the entire cohort. Areas under the receiver operating characteristic curves (AUC) were evaluated, and Hosmer-Lemeshow goodness-of-fit tests were used to assess validation model fit.
Of 5,389 patients, 1,182 (21.9%) experienced at least one complication of the combined endpoint. Male gender, open surgery, ASA ≥3, wound class ≥3, ileostomy, surgical duration >3 hours, and perioperative IV fluids >3 L all had significantly greater odds of the combined endpoint in the parsimonious multivariable model (all P < .05). The reduced model considering only the 4 variables with the highest OR (>1.5) contained open surgery, ASA ≥3, wound class ≥3, and surgical duration ≥3 hours as predictors (all P < .05, AUC of 0.65; 95% CI 0.63, 0.68). Both the parsimonious model and the reduced model demonstrated no lack of fit in the validation cohort.
The suggested score composed of preand intraoperative items may help physicians decide on patients' same-day discharge after colorectal resection.
Mots-clé
Ambulatory Surgical Procedures/adverse effects, Clinical Decision-Making, Colon/surgery, Colonic Diseases/surgery, Female, Humans, Logistic Models, Male, Middle Aged, Patient Discharge, Postoperative Complications/prevention & control, Rectal Diseases/surgery, Rectum/surgery, Retrospective Studies, Risk Assessment/methods
Pubmed
Web of science
Création de la notice
21/09/2021 12:58
Dernière modification de la notice
27/07/2023 5:57