Conditioning stimulus can influence an external urethral sphincter contraction evoked by a magnetic stimulation.

Détails

ID Serval
serval:BIB_271CBEA7049E
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Conditioning stimulus can influence an external urethral sphincter contraction evoked by a magnetic stimulation.
Périodique
Neurourology and Urodynamics
Auteur(s)
Wefer B., Reitz A., Knapp P.A., Bannowsky A., Juenemann K.P., Schurch B.
ISSN
0733-2467 (Print)
ISSN-L
0733-2467
Statut éditorial
Publié
Date de publication
2005
Volume
24
Numéro
4
Pages
311-317; discussion 318
Langue
anglais
Notes
Publication types: Clinical Trial ; Journal Article ; Research Support, Non-U.S. Gov't Publication Status: ppublish
Résumé
AIMS: To study the effect of a conditioning stimulus on an external urethral sphincter (EUS)contraction evoked by a magnetic stimulation at different time intervals.
METHODS: Seven healthy male volunteers underwent EUS pressure measurement. At baseline, magnetic stimulation of the lumbosacral spinal cord above the motor threshold was performed and evoked EUS pressure responses were recorded. The lumbosacral magnetic stimulation was repeated with same intensity, while a selective electrical dorsal penile nerve stimulation below the bulbocavernosus reflex (BCR) threshold was preceding at five different intervals (10, 20, 30, 50, 100 msec). The protocol was performed with empty and full bladder (BLA), and baseline responses were statistically compared to those with combined stimulation.
RESULTS: When the dorsal penile nerve electrical stimulation preceded the lumbosacral magnetic stimulation by 20 msec (P=0.0048), 50 msec (P=0.0039), or 100 msec (P=0.0002), the amplitudes of the EUS pressure response with empty BLA were significantly reduced compared to lumbosacral magnetic stimulation alone. With a filled BLA, the amplitudes of the EUS were significantly reduced only at an interval of 50 msec (P<0.0001).
CONCLUSIONS: A conditional sensory pudendal stimulation seems to have the capacity to inhibit the external urethral sphincter contraction induced by a magnetic stimulation. The inhibitory effect seems to depend on the latency between the peripheral and lumbosacral stimulation as well as on the degree of BLA filling. It remains to be proved if the neuromodulative effect of the conditional stimulus occurs at a spinal or supraspinal level.
Mots-clé
Adult, Conditioning (Psychology), Electric Stimulation, Electromagnetic Fields, Humans, Male, Muscle Contraction/physiology, Muscle, Smooth/innervation, Muscle, Smooth/physiology, Neurons, Afferent/physiology, Penis/innervation, Pressure, Reflex/physiology, Urethra/physiology, Urinary Bladder/innervation, Urinary Bladder/physiology, Urodynamics/physiology
Pubmed
Web of science
Création de la notice
05/11/2014 13:12
Dernière modification de la notice
20/08/2019 14:06
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