Physiopathologie cardio-vasculaire des hormones ovariennes. [Cardiovascular physiopathology of ovarian hormones]
Détails
ID Serval
serval:BIB_26DAB2662F1E
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Synthèse (review): revue aussi complète que possible des connaissances sur un sujet, rédigée à partir de l'analyse exhaustive des travaux publiés.
Collection
Publications
Institution
Titre
Physiopathologie cardio-vasculaire des hormones ovariennes. [Cardiovascular physiopathology of ovarian hormones]
Périodique
Schweizerische Rundschau fur Medizin Praxis
ISSN
1013-2058
Statut éditorial
Publié
Date de publication
01/1997
Volume
86
Numéro
5
Pages
138-44
Notes
English Abstract
Journal Article
Review --- Old month value: Jan 28
Journal Article
Review --- Old month value: Jan 28
Résumé
Epidemiological data indicate that women are less likely to suffer from coronary heart disease (CHD) than men of the same age. This difference vanishes however after menopause suggesting that it is the hormones produced by the ovaries that are responsible for the relative cardioprotection that women enjoy before menopause. In spite of the favorable impact of oral estrogen treatments on the lipid profile it is believed today that estrogens act mainly through direct effects on vessels. Estrogens have vasodilative properties, exert anti proliferative effects on the endothelium and alter the response of vessels to various stimuli (vaso-reactivity) such as Acetylcholine (Ach). Direct assessment of large vessel wall thickness or Intima Media Thickness (IMT) is considered as the most predictive parameter of cardiovascular risk today and may serve to single out women who must receive HRT for cardiovascular reasons.
Mots-clé
Adolescent
Adult
Aged
Aged, 80 and over
Animals
Cardiovascular Diseases/*prevention & control
Cardiovascular System/*drug effects
Child
*Estrogen Replacement Therapy
Estrogens/pharmacology
Female
Humans
Lipids/blood
Macaca fascicularis
Male
Middle Aged
Muscle, Smooth, Vascular/drug effects
Risk Factors
Vascular Resistance/drug effects
Vasodilation/drug effects
Pubmed
Création de la notice
28/02/2008 12:36
Dernière modification de la notice
20/08/2019 14:05