L'immunothérapie des carcinomes epidermoïdes de la sphère ORL [Immunotherapy for head and neck squamous cell carcinoma]

Détails

ID Serval
serval:BIB_25A3BBEBE765
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Synthèse (review): revue aussi complète que possible des connaissances sur un sujet, rédigée à partir de l'analyse exhaustive des travaux publiés.
Collection
Publications
Institution
Titre
L'immunothérapie des carcinomes epidermoïdes de la sphère ORL [Immunotherapy for head and neck squamous cell carcinoma]
Périodique
Revue médicale suisse
Auteur(s)
Bron L., Romero P.
ISSN
1660-9379
Statut éditorial
Publié
Date de publication
2006
Volume
2
Numéro
81
Pages
2216-2219
Langue
français
Notes
Publication types: English Abstract ; Journal Article ; Review
Publication Status: ppublish
Résumé
In the past decades, prognosis of head and neck squamous cell carcinoma (HNSCC) has not improved despite substantial progress in treatment options. Since antitumoral immunity was described, immunotherapy has shown promising results as an adjunctive treatment in various cancer types. Tumor-associated antigens (TAAs) have been identified and shown to stimulate selective T-cell-mediated antitumoral immune response. This article briefly reviews the work done in the field of immunotherapy of HNSCC in the past few years. It gives confidence that immunotherapy may play an important role in the treatment of head and neck squamous cell carcinoma. Among various TAAs, the family of cancer testis antigens (CTAs) may be promising candidates for specific immune therapy in HNSCC. Ongoing studies will confirm whether CTAs may generate an immune response in clinical vaccine trials.
Mots-clé
Carcinoma, Squamous Cell/therapy, Head and Neck Neoplasms/therapy, Humans, Immunotherapy
Pubmed
Création de la notice
28/01/2008 12:27
Dernière modification de la notice
20/08/2019 14:04
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