The first episode psychosis outcome study (FEPOS): pre-morbid and baseline characteristics of 704 first episode psychosis patients treated in EPPIC between 1998 and 2000

Détails

ID Serval
serval:BIB_256DA69AC959
Type
Actes de conférence (partie): contribution originale à la littérature scientifique, publiée à l'occasion de conférences scientifiques, dans un ouvrage de compte-rendu (proceedings), ou dans l'édition spéciale d'un journal reconnu (conference proceedings).
Sous-type
Abstract (résumé de présentation): article court qui reprend les éléments essentiels présentés à l'occasion d'une conférence scientifique dans un poster ou lors d'une intervention orale.
Collection
Publications
Institution
Titre
The first episode psychosis outcome study (FEPOS): pre-morbid and baseline characteristics of 704 first episode psychosis patients treated in EPPIC between 1998 and 2000
Auteur(s)
Conus Philippe, Cotton Sue, Graf Schimmelmann Benno, McGorry Patrick D., Lambert Martin
ISBN
0920-9964
Statut éditorial
Publié
Date de publication
2006
Peer-reviewed
Oui
Volume
81
Série
Schizophrenia Research
Pages
232
Langue
anglais
Notes
SAPHIRID:61450
Résumé
Background: Study of psychotic disorders is hampered by many potential baises that can be avoided in first episode psychosis (FEP) samples. However, very few studies are based on epidemiological samples. Our aim is to describe premorbid and baseline clinical and socio-demographic characteristics of a large epidemiological sample of FEP.
Methods: Medical records review of patients treated at EPPIC between 1998 and 2000.
Results: 704 files were assessed. Pre-morbid evaluation revealed high rates of substance use disorder (74.%), history of psychiatric disorder (46%), traumatic events (68%), suicide attempts (14%) and family history of psychiatric illness (55%). Baseline characteristics revealed high intensity of illness, high prevalence of lack of insight and high rate of co-morbidity.
Conclusions: Majority of subjects have gone through either traumatic events or episodes of mental illness before treatment for FEP. Such elements must be considered when designing treatment approaches since a too narrow focus on positive psychotic symptoms will inevitably lead to incomplete treatment. Additionally, early intervention programs need sufficient range of ressources to address the multiples challenges presented by FEP patients such as co-morbidities and high severity of illness. Finally, observation that patients in this cohort developed important level of functional impairment before FEP treatment despite a relatively short duration of untreated psychosis suggests that while early detection of FEP is a necessary step in early intervention, it may not be a sufficient strategy to limit functional impairment and that efforts aimed at identifying people during the prodromal phase of psychotic disorders should be pursued.
Création de la notice
10/03/2008 11:00
Dernière modification de la notice
20/08/2019 14:03
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