Photodynamic therapy with verteporfin for subfoveal choroidal neovascularization secondary to toxoplasmic chorioretinal scar.

Détails

ID Serval
serval:BIB_24821A85EDDE
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Etude de cas (case report): rapporte une observation et la commente brièvement.
Collection
Publications
Institution
Titre
Photodynamic therapy with verteporfin for subfoveal choroidal neovascularization secondary to toxoplasmic chorioretinal scar.
Périodique
Klinische Monatsblätter für Augenheilkunde
Auteur(s)
Nessi F., Guex-Crosier Y., Ambresin A., Zografos L.
ISSN
0023-2165
Statut éditorial
Publié
Date de publication
05/2004
Peer-reviewed
Oui
Volume
221
Numéro
5
Pages
371-373
Langue
anglais
Résumé
BACKGROUND: To assess the effect of photodynamic therapy in the treatment of subfoveal choroidal neovascularization consecutive to a toxoplasmic chorioretinal scar. HISTORY AND SIGNS: Three patients with a previous history of toxoplasmic chorioretinal scar noticed a decrease in visual acuity and metamorphopsia. Fundus examination and fluorescein angiography revealed the presence of subfoveal choroidal neovascularization at the edge of the toxoplasmic chorioretinal scar. THERAPY AND OUTCOME: The first patient, aged 78, was treated by photodynamic therapy followed by three subsequent treatments of feeder vessel by laser photocoagulation. Visual acuity decreased during follow-up in the presence of recurrence of choroidal neovascularization and subretinal fibrosis. The second patient, a 20-year-old lady, was treated with three sessions of photodynamic therapy for a subfoveal choroidal neovascularization related to a toxoplasmic scar. Visual acuity was stabilized on the last follow-up visit at 0.3. The third patient, aged 53, received four treatments with photodynamic therapy at an interval of 3 - 4 months. choroidal neovascularization was stabilized and the last visual acuity was 0.2. CONCLUSIONS: This preliminary report suggests that photodynamic therapy with verteporfine may be an effective therapeutic modality for subfoveal choroidal neovascularization related to a toxoplasmic chorioretinal scar. Further assessment is needed in order to confirm this preliminary findings.
Mots-clé
Adult, Aged, Choroidal Neovascularization, Cicatrix, Female, Fluorescein Angiography, Fovea Centralis, Hematoporphyrin Photoradiation, Humans, Male, Middle Aged, Porphyrins, Retinitis, Toxoplasmosis, Ocular, Treatment Outcome
Pubmed
Web of science
Création de la notice
28/01/2008 13:10
Dernière modification de la notice
20/08/2019 13:02
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