Primary Sarcomatoid Carcinoma of the Lung: Radiometabolic ((18)F-FDG PET/CT) Findings and Correlation with Clinico-Pathological and Survival Results.

Détails

ID Serval
serval:BIB_23DF11466C48
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Primary Sarcomatoid Carcinoma of the Lung: Radiometabolic ((18)F-FDG PET/CT) Findings and Correlation with Clinico-Pathological and Survival Results.
Périodique
Lung
Auteur(s)
Rapicetta C., Lococo F., Stefani A., Rossi G., Ricchetti T., Filice A., Franceschetto A., Treglia G., Paci M.
ISSN
1432-1750 (Electronic)
ISSN-L
0341-2040
Statut éditorial
Publié
Date de publication
08/2016
Peer-reviewed
Oui
Volume
194
Numéro
4
Pages
653-657
Langue
anglais
Notes
Publication types: Journal Article
Publication Status: ppublish
Résumé
Pulmonary sarcomatoid carcinoma (PSC) is a very rare and uninvestigated subtype of non-small cell lung cancer (NSCLC).
The aims of this study were to define the radiometabolic features (by (18)F-FDG PET/CT) in a bi-centric cohort of 49 PSC patients and to explore their relation with clinico-pathological characteristics and long-term survival results after surgical treatment.
There were 40 males and 9 females aged 65.2 ± 10.47 years. Overall long-term survival was 26.7 % at 5 years. Mean and median values of SUVmax were 15.21 and 15, respectively (SD ±5.5). Performing an age-, gender- and staging-matched analysis comparing PSC Stage-I only with a cohort of Stage-I NSCLC (n = 93), we observed significantly higher SUVmax values in PSC group (15.11 vs 7.66, p = 0.001).
No differences in terms of SUVmax were found with regard to tumour dimensions, histology (pure vs mixed, pleomorphic vs others), pathological stage and pattern of recurrence. P-stage, surgical radicality, vascular/lymphatic invasion but not SUVmax affected long-term survival in PSC.

Mots-clé
PET, Pulmonary sarcomatoid carcinoma, Rare lung tumours, SUV, Survival
Pubmed
Web of science
Création de la notice
20/08/2017 17:36
Dernière modification de la notice
20/08/2019 14:01
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