Cancer risk in women with previous breast cancer

Détails

ID Serval
serval:BIB_22B43C540BA0
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Titre
Cancer risk in women with previous breast cancer
Périodique
Annals of Oncology
Auteur⸱e⸱s
Levi Fabio, Te Van Cong, Randimbison Lalao, La Vecchia Carlo
ISSN
0923-7534
Statut éditorial
Publié
Date de publication
2003
Volume
14
Numéro
1
Pages
71-73
Notes
Réf. IUMSP: R 03/03 SAPHIRID:44919
Résumé
BACKGROUND: Excess risks of several second neoplasms following breast cancer have been reported. However, these risks have still to be quantified. PATIENTS AND METHODS: We considered 9,729 breast cancer patients registered by the Swiss Cancer Registries of Vaud and Neuchatel (covering about 786,000 inhabitants) and followed up from 1974 to 1998. RESULTS: Overall, 443 second primary neoplasms (other than second primary breast cancers) were observed versus 389 expected [standardised incidence ratio (SIR): 1.14; 95% confidence interval (CI) 1.04-1.25]. The SIRs were above unity for endometrium (SIR = 1.5), ovary (1.3), colorectum (1.1), gallbladder (1.4), cutaneous malignant melanoma (1.4), kidney (1.4), lymphomas (1.4) and leukaemias (1.2), as well as for selected tobacco-related neoplasms. The largest excess risk was found for soft tissue sarcomas (STS) with 10 cases observed versus 3.1 expected (SIR = 3.2; 95% CI 1.5-5.9). Of these, eight occurred in potentially irradiated areas. CONCLUSIONS: This analysis confirms the existence of a modest excess in several neoplasms occurring after breast cancer. The substantial excess of STS confirms the strong association between irradiation and STS. [authors]
Mots-clé
Breast Neoplasms , Neoplasms, Second Primary
Pubmed
Web of science
Création de la notice
06/03/2008 15:31
Dernière modification de la notice
20/08/2019 13:00
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