Temporal pole MRI abnormalities in temporal lobe epilepsy
Détails
ID Serval
serval:BIB_21DEC2E4A313
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Synthèse (review): revue aussi complète que possible des connaissances sur un sujet, rédigée à partir de l'analyse exhaustive des travaux publiés.
Collection
Publications
Institution
Titre
Temporal pole MRI abnormalities in temporal lobe epilepsy
Périodique
Epileptic Disord
ISSN
1294-9361 (Print)
ISSN-L
1294-9361
Statut éditorial
Publié
Date de publication
09/2002
Volume
4 Suppl 1
Pages
S33-9
Langue
anglais
Notes
Ryvlin, Philippe
Coste, Sebastien
Hermier, Marc
Mauguiere, Francois
eng
France
Epileptic Disord. 2002 Sep;4 Suppl 1:S33-9.
Coste, Sebastien
Hermier, Marc
Mauguiere, Francois
eng
France
Epileptic Disord. 2002 Sep;4 Suppl 1:S33-9.
Résumé
Magnetic resonance imaging (MRI) demonstrates an abnormal aspect of the temporo-polar region in 1/3 to 2/3 of patients suffering from cryptogenic temporal lobe epilepsy. This abnormal aspect is described as a white matter increased T2 signal, resulting in a loss of gray-white matter demarcation, often associated with atrophy, as recently confirmed by quantitative volumetric measurements. These temporo-polar MRI findings appear to correctly lateralize the epileptogenic temporal lobe with a very high specificity, and have never been reported in extra-temporal lobe epilepsy nor in control subjects. They are usually associated with MRI signs of hippocampal sclerosis, but the two conditions seem to be partly distinct from a pathophysiological point of view. Pathological correlates of temporo-polar white matter increased T2 signal are controversial, but the role of an abnormal myelin seems more likely than that of ectopic neurons. A myelin dysfunction would also be consistent with the correlation observed between lateral temporal hypometabolism and temporo-polar MRI abnormalities. Whether or not these MRI findings are associated with a better seizure outcome following temporal lobectomy remains a debated issue.
Mots-clé
Atrophy/pathology/surgery, Epilepsy, Temporal Lobe/*diagnosis/surgery, Flumazenil/pharmacokinetics, GABA Modulators/pharmacokinetics, Humans, *Magnetic Resonance Imaging, Temporal Lobe/*abnormalities/metabolism/surgery, Tomography, Emission-Computed
Pubmed
Création de la notice
29/11/2018 13:37
Dernière modification de la notice
20/08/2019 13:58