Abnormal monitoring of inner speech: a physiological basis for auditory hallucinations.

Détails

ID Serval
serval:BIB_21832629B0CF
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Abnormal monitoring of inner speech: a physiological basis for auditory hallucinations.
Périodique
Lancet
Auteur⸱e⸱s
McGuire P.K., Silbersweig D.A., Wright I., Murray R.M., David A.S., Frackowiak R.S., Frith C.D.
ISSN
0140-6736 (Print)
ISSN-L
0140-6736
Statut éditorial
Publié
Date de publication
1995
Volume
346
Numéro
8975
Pages
596-600
Langue
anglais
Notes
Publication types: Comparative Study ; Journal Article ; Research Support, Non-U.S. Gov'tPublication Status: ppublish
Résumé
Auditory verbal hallucinations ("voices") are thought to arise from a disorder of inner speech (thinking in words). We examined the neural correlates of tasks which involve inner speech in subjects with schizophrenia who hear voices (hallucinators), subjects with schizophrenia who do not (nonhallucinators), and normal controls. There were no differences between hallucinators and controls in regional cerebral blood flow during thinking in sentences. However, when imagining sentences being spoken in another person's voice--which entails both the generation and monitoring of inner speech--hallucinators had a normal left frontal response, but reduced activation in the left middle temporal gyrus and the rostral supplementary motor area, regions which were activated by both normal subjects and nonhallucinators (p < 0.001). These findings suggest that a predisposition to verbal hallucinations is associated with a failure to activate areas concerned with the monitoring of inner speech.
Mots-clé
Adult, Auditory Perceptual Disorders/complications, Auditory Perceptual Disorders/diagnosis, Cerebrovascular Circulation, Hallucinations/etiology, Hallucinations/physiopathology, Humans, Male, Schizophrenia/complications, Speech Perception/physiology, Tomography, Emission-Computed
Pubmed
Web of science
Création de la notice
16/09/2011 19:35
Dernière modification de la notice
20/08/2019 12:58
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