Major impact of body position on arterial stiffness indices derived from radial applanation tonometry in pregnant and nonpregnant women.

Détails

ID Serval
serval:BIB_2157440047D5
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Titre
Major impact of body position on arterial stiffness indices derived from radial applanation tonometry in pregnant and nonpregnant women.
Périodique
Journal of Hypertension
Auteur(s)
Jaccoud L., Rotaru C., Heim A., Liaudet L., Waeber B., Hohlfeld P., Feihl F.
ISSN
1473-5598 (Electronic)
ISSN-L
0263-6352
Statut éditorial
Publié
Date de publication
2012
Peer-reviewed
Oui
Volume
30
Numéro
6
Pages
1161-1168
Langue
anglais
Notes
Publication types: Comparative Study ; Journal Article ; Research Support, Non-U.S. Gov't
Résumé
OBJECTIVE: To evaluate the impact of body position on the arterial stiffness indices provided by radial applanation tonometry in pregnant and nonpregnant women.
METHODS: Twenty-four young women (18-30 years) in the third trimester of a normal pregnancy and 20 healthy nonpregnant women of the same age were enrolled. In each, applanation tonometry was carried out in the sitting and supine position. The following stiffness indices were analyzed: systolic augmentation index (sAix), sAix adjusted for heart rate (sAix@75) and diastolic augmentation index (dAix), all expressed in % of central aortic pulse pressure.
RESULTS: The sAix was apparently not influenced by body position, but the transition from seated to supine was associated with a substantial decrease in heart rate. When correcting for this confounder by calculating the sAix@75, systolic augmentation was substantially lower when individuals were supine (mean ± SD: nonpregnant 3.0 ± 14.4%, pregnant 8.8 ± 9.7%) than when they were sitting (nonpregnant 5.7 ± 13.0%, pregnant 11.1 ± 83%, P = 0.005 supine vs. seated in both study groups, P > 0.2 for pregnant vs. nonpregnant). The influence of body position on the dAix went in the opposite direction (supine: nonpregnant 9.7 ± 6.6%, pregnant 4.4 ± 3.5%; seated: nonpregnant 7.7 ± 5.8%, pregnant 3.3 ± 2.4%, P < 0.00001 supine vs. seated in both study groups, P = 0.001 for pregnant vs. nonpregnant).
CONCLUSION: Body position has a major impact on the pattern of central aortic pressure augmentation by reflected waves in healthy young women examined either during third trimester pregnancy or in the nonpregnant state.
Mots-clé
Arteries/physiopathology, Case-Control Studies, Female, Humans, Manometry, Posture, Pregnancy
Pubmed
Web of science
Création de la notice
10/07/2012 12:09
Dernière modification de la notice
20/08/2019 12:57
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