Comparative in vitro potency of gemifloxacin and fluoroquinolones against recent European clinical isolates from a global surveillance study.

Détails

ID Serval
serval:BIB_20048
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Etude de cas (case report): rapporte une observation et la commente brièvement.
Collection
Publications
Institution
Titre
Comparative in vitro potency of gemifloxacin and fluoroquinolones against recent European clinical isolates from a global surveillance study.
Périodique
European Journal of Clinical Microbiology & Infectious Diseases
Auteur(s)
Hoban D.J., Bouchillon S.K., Johnson J.L., Zhanel G.G., Butler D.L., Miller L.A., Poupard J.A.
ISSN
0934-9723
Statut éditorial
Publié
Date de publication
2001
Volume
20
Numéro
11
Pages
814-819
Langue
anglais
Notes
Publication types: Comparative Study ; Journal Article ; Research Support, Non-U.S. Gov't
Résumé
Gemifloxacin, a new fluoroquinolone with enhanced activity against gram-positive aerobes, was compared to ciprofloxacin, levofloxacin and ofloxacin against 21,464 recent isolates from 16 European countries. Gemifloxacin was the most potent fluoroquinolone against streptococci including penicillin-, macrolide- and ciprofloxacin-resistant Streptococcus pneumoniae, Staphylococcus aureus, coagulase-negative staphylococci, Acinetobacter spp., Haemophilus spp. and Moraxella catarrhalis. This drug was more potent than or comparable to ciprofloxacin against members of the family Enterobacteriaceae, Burkholderia cepacia, Pseudomonas aeruginosa and Stenotrophomonas maltophilia. Gemifloxacin is a promising fluoroquinolone with potent in vitro activity.
Mots-clé
Anti-Infective Agents/pharmacology, Ciprofloxacin/pharmacology, Drug Resistance, Microbial, Drug Resistance, Multiple, Europe, Fluoroquinolones, Gram-Negative Bacteria/drug effects, Gram-Negative Bacteria/isolation & purification, Gram-Positive Bacteria/drug effects, Gram-Positive Bacteria/isolation & purification, Humans, Microbial Sensitivity Tests, Naphthyridines/pharmacology, Ofloxacin/pharmacology
Pubmed
Web of science
Création de la notice
19/11/2007 12:14
Dernière modification de la notice
20/08/2019 12:55
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