Difficult tracheal intubation in neonates and infants. NEonate and Children audiT of Anaesthesia pRactice IN Europe (NECTARINE): a prospective European multicentre observational study.
Détails
ID Serval
serval:BIB_1E0818DD5105
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Titre
Difficult tracheal intubation in neonates and infants. NEonate and Children audiT of Anaesthesia pRactice IN Europe (NECTARINE): a prospective European multicentre observational study.
Périodique
British journal of anaesthesia
Collaborateur⸱rice⸱s
NECTARINE Group of the European Society of Anaesthesiology Clinical Trial Network, AUSTRIA (Maria Vittinghoff), BELGIUM (Francis Veyckemans), CROATIA (Sandra Kralik), CZECH REPUBLIC (Jiří Žurek), DENMARK (Tom Hansen), ESTONIA (Reet Kikas), FINLAND (Tuula Manner), FRANCE (Christophe Dadure, Anne Lafargue), GERMANY (Karin Becke, Claudia Hoehne), GREECE (Anna Malisiova), HUNGARY (Andrea Székely), IRELAND (Brendan O'Hare), ITALY (Nicola Disma), LATVIA (Zane Straume), LITHUANIA (Laura Lukosiene), LUXEMBOURG (Bernd Schmitz), MALTA (Francis Borg), NETHERLANDS (Jurgen de Graaff), NORWAY (Wenche B Boerke), POLAND (Marzena Zielinska), PORTUGAL (Maria Domingas Patuleia), ROMANIA (Radu Tabacaru), SERBIA (Dusica Simic), SLOVAKIA (Miloslav Hanula), SLOVENIA (Jelena Berger), SPAIN (Ignacio Gálvez Escalera), SWEDEN (Albert Castellheim), SWITZERLAND (Walid Habre), TURKEY (Dilek Özcengiz - Zehra Hatipoğlu), UKRAINE (Dmytro Dmytriiev), UNITED KINGDOM (Thomas Engelhardt, Suellen Walker), Management Team
Contributeur⸱rice⸱s
Breschan C., Likar R., Platzer M., Edelman I., Eger J., Heschl S., Messerer B., Vittinghof M., Kroess R., Stichlberger M., Kahn D., Pirotte T., Pregardien C., Veyckemans F., Stevens F., Berghmans J., Bauters A., De Baerdemaeker L., De Hert S., Lapage K., Parashchanka A., Van Limmen J., Wyffels P., Lauweryns J., Najafi N., Vundelinckx J., Butković D., Kerovec Sorić I., Kralik S., Markić A., Azman J., Markic J., Pupacic D., Frelich M., Reimer P., Urbanec R., Cajková P., Mixa V., Sedláčková Y., Knoppová L., Zlámalová Neé Květoňová A., Vavřina M., Žurek J., Hansen T., Afshari A., Bille A.B., Ellekvist M., Ilmoja M.L., Moor R., Kikas R., Väli M., Kallio K., Reponen E., Suominen P., Suvanto S., Vähätalo R., Kokki H., Kokki M., Harju J., Kokkonen M., Vieri J., Manner T., Amory C., Ludot H., Bert D., Godart J., Laffargue A., Dupont H., Urbina B., Baujard C., Roulleau P., Staiti G., Bordes M., Nouette Gaulain K., Hamonic Y., Semjen F., Jacqmarcq O., Lejus-Bourdeau C., Magne C., Petry L., Ros L., Zang A., Bennis M., Coustets B., Fesseau R., Constant I., Khalil E., Sabourdin N., Audren N., Descarpentries T., Fabre F., Legrand A., Druot E., Orliaguet G., Sabau L., Uhrig L., de la Brière F., Jonckheer K., Mission J.P., Scordo L., Couchepin C., Dadure C., De la Arena P., Hertz L., Pirat P., Sola C., Bellon M., Dahmani S., Julien-Marsollier F., Michelet D., Depret-Donatien V., Lesage A., Kaufmann J., Laschat M., Wappler F., Becke K., Brunner L., Oppenrieder K., Badelt G., Hochmuth K., Koller B., Reil A., Richter S., Fischer T., Diers A., Schorer C., Weyland A., Cohausz R., Kretz F.J., Löffler M., Wilbs M., Hoehne C., Ulrici J., Goeters C., Flinspach A., Klages M., Lindau S., Messroghli L., Zacharowski K., Eisner C., Mueller T., Richter D., Schäfer M., Weigand M., Weiterer S., Ochsenreiter M., Schöler M., Terboven T., Eggemann I., Haussmann S., Leister N., Menzel C., Trieschmann U., Yücetepe S., Keilig S., Kranke P., Jelting Y., Baehner T., Ellerkmann R., Ghamari S., Neumann C., Söhle M., Chloropoulou P., Ntritsou V., Papagiannopoulou P., Garini E., Karafotia A., Mammi P., Bali E., Iordanidou D., Malisiova A., Polyzoi A., Tsiotou A., Sapi E., Székely E., Kosik N., Maráczi V., Schnur J., Csillag J., Gál J., Göbl G., Hauser B., Petróczy A., Tövisházi G., Blain S., Gallagher S., Harte S., Jackson M., Meehan E., Nawoor Z., O'Hare B., Ross M., Lerro D., Astuto M., Grasso C., Scalisi R., Frasacco G., Lenares E., Leone R., Grazzini M., Minardi C., Zadra N., Cinnella G., Cotoia A., Galante D., De Lorenzo B., Kuppers B., Bottazzi G., Caramelli F., Mondardini M.C., Rossetti E., Picardo S., Vittori A., Camporesi A., Wolfler A., Calderini E., Colantonio L.B., Finamore S.A., Porro G.A., Bonfiglio R., Disma N., Kotzeva S., Mameli L., Mattioli G., Micalizzi C., Montaguti A., Pistorio A., Zanaboni C., Guddo A., Neba G.R., Favarato M., Locatelli B.G., Maffioletti M., Sonzogni V., Garra R., Sammartino M., Sbaraglia F., Cortegiani A., Moscarelli A., Attanasi E., Tesoro S., Agapiti C., Pinzoni F., Vezzoli C., Bilotta F., Barzdina A., Straume Z., Zundane A., Lukosiene L., Maraulaite I., Razlevice I., Schmitz B., Mifsud S., Aehling C., Allison C., De Boer R., Emal D., Stevens M., Buitenhuis M., de Graaff J., De Liefde I., Machotta A., Scoones G., Staals L., Tomas J., Van der Knijff-van Dortmont A., Veldhuizen M., Alders D., Buhre W., Schafrat E., Schreiber J., Vermeulen P.M., Hendriks M., Lako S., Voet-Lindner M., Pieters B., Scheffer G.J., Tielens L., Absalom A.R., Bergsma M., De Ruiter J., Meier S., Volkers M., Zweers T., Beukers A.M., Boer C., Dertinger J., Numan S., Van Zaane B., Boerke W.B., Ekiz N., Stensrud K., Drage I.M., Isern E.R., Bartkowska-Sniatkowska A., Grzeskowiak M., Juzwa-Sobieraj M., Rosada-Kurasińska J., Baranowski A., Jakubowska K., Lewandowska D., Mierzewska-Schmidt M., Sawicki P., Urban-Lechowicz M., Przemyslaw P., Zielinska M., Leal T., Soares M., Pina P., Pinho S., Patuleia M.D., Esteves C.C., Salgado H., Santos M.J., Badeti R., Cindea I., Oana L., Gurita A., Ilie L., Mocioiu G., Tabacaru R., Trante I., Munteanu V., Morariu M., Nyíri E., Budic I., Marjanovic V., Drašković B., Pandurov M., Ilic J., Mandras A., Rados Z., Stankovic N., Suica M., Vasiljevic S., Knezevic M., Milojevic I., Petrov I., Puric Racic S., Simic D., Simic I., Stevic M., Vulicevic I., Cabanová B., Hanula M., Berger J., Janjatovic D., Pirtovšek Štupnik Š., Méndez D., Pino G., Rubio P., Izquierdo A., López S., González Serrano C., Cebrián J., Peleteiro A., Del Rey de Diego P., Martínez García E., Tormo de Las Heras C., Troncoso Montero P., Arbona C., Artés D., Chamizo A., Serrano S., Suarez Comas M., Escribá F., Auli C., Pérez Pardo O., Sierra Biddle N., Suárez Castaño C., Villalobos Rico M.I., Manrique Muñoz S., García Martínez I., Montferrer Estruch N., Vilardell Ortíz E., Poves-Álvarez R., Kohn I., Lindestam U., Reinhard J., Castellheim A., Sandström K., Bengt S., Dörenberg R., Frykholm P., Garcia M., Kvarnström A., Pontén E., Bruelisauer T., Erdoes G., Kaiser H., Marchon M., Riva T., Seiler S., Bögli Y., Dolci M., Marcucci C., Habre W., Pichon I., Vutskits L., Casutt M., Hölzle M., Hurni T., Jöhr M., Malär A.U., Mauch J., Erb T., Oeinck K., Akin M., Keskin G., Senayli Y., Kaya G., Kendigelen P., Tutuncu A.Ç., Hatipoğlu Z., Özcengiz D., Erdost H.A., Öçmen E., Olguner Ç., Ayanoglu H., Dincer P.C., Umuroglu T., Azizoglu M., Birbiçer H., Doruk N., Sagun A., Baris S., Dmytriiev D., Kuchi S., Masip N., Brooks P., Hare A., Ahmad N., Casey M., De Silva S., Dobby N., Krishnan P., Sogbodjor L.A., Walker E., Walker S., King S., Nicholson K., Quinney M., Stevens P., Blevin A., Giombini M., Goonasekera C., Adil S., Bew S., Bodlani C., Gilpin D., Jinks S., Malarkkan N., Miskovic A., Pad R., Wolfe Barry J., Abbott J., Armstrong J., Cooper N., Crate L., Emery J., James K., King H., Martin P., Scalia Catenacci S., Bomont R., Smith P., Mele S., Verzelloni A., Dix P., Bell G., Gordeva E., McKee L., Ngan E., Scheffczik J., Tan L.E., Worrall M., Cassar C., Goddard K., Barlow V., Oshan V., Shah K., Bell S., Daniels L., Gandhi M., Pachter D., Perry C., Robertson A., Scott C., Waring L., Barnes D., Childs S., Norman J., Sunderland R., Julia D., Prisca F., Pierre H., Sarah H., Brigitte L., Benoît P., Katalin V.
ISSN
1471-6771 (Electronic)
ISSN-L
0007-0912
Statut éditorial
Publié
Date de publication
06/2021
Peer-reviewed
Oui
Volume
126
Numéro
6
Pages
1173-1181
Langue
anglais
Notes
Publication types: Journal Article ; Multicenter Study ; Observational Study
Publication Status: ppublish
Publication Status: ppublish
Résumé
Neonates and infants are susceptible to hypoxaemia in the perioperative period. The aim of this study was to analyse interventions related to anaesthesia tracheal intubations in this European cohort and identify their clinical consequences.
We performed a secondary analysis of tracheal intubations of the European multicentre observational trial (NEonate and Children audiT of Anaesthesia pRactice IN Europe [NECTARINE]) in neonates and small infants with difficult tracheal intubation. The primary endpoint was the incidence of difficult intubation and the related complications. The secondary endpoints were the risk factors for severe hypoxaemia attributed to difficult airway management, and 30 and 90 day outcomes.
Tracheal intubation was planned in 4683 procedures. Difficult tracheal intubation, defined as two failed attempts of direct laryngoscopy, occurred in 266 children (271 procedures) with an incidence (95% confidence interval [CI]) of 5.8% (95% CI, 5.1-6.5). Bradycardia occurred in 8% of the cases with difficult intubation, whereas a significant decrease in oxygen saturation (SpO <sub>2</sub> <90% for 60 s) was reported in 40%. No associated risk factors could be identified among co-morbidities, surgical, or anaesthesia management. Using propensity scoring to adjust for confounders, difficult anaesthesia tracheal intubation did not lead to an increase in 30 and 90 day morbidity or mortality.
The results of the present study demonstrate a high incidence of difficult tracheal intubation in children less than 60 weeks post-conceptual age commonly resulting in severe hypoxaemia. Reassuringly, the morbidity and mortality at 30 and 90 days was not increased by the occurrence of a difficult intubation event.
NCT02350348.
We performed a secondary analysis of tracheal intubations of the European multicentre observational trial (NEonate and Children audiT of Anaesthesia pRactice IN Europe [NECTARINE]) in neonates and small infants with difficult tracheal intubation. The primary endpoint was the incidence of difficult intubation and the related complications. The secondary endpoints were the risk factors for severe hypoxaemia attributed to difficult airway management, and 30 and 90 day outcomes.
Tracheal intubation was planned in 4683 procedures. Difficult tracheal intubation, defined as two failed attempts of direct laryngoscopy, occurred in 266 children (271 procedures) with an incidence (95% confidence interval [CI]) of 5.8% (95% CI, 5.1-6.5). Bradycardia occurred in 8% of the cases with difficult intubation, whereas a significant decrease in oxygen saturation (SpO <sub>2</sub> <90% for 60 s) was reported in 40%. No associated risk factors could be identified among co-morbidities, surgical, or anaesthesia management. Using propensity scoring to adjust for confounders, difficult anaesthesia tracheal intubation did not lead to an increase in 30 and 90 day morbidity or mortality.
The results of the present study demonstrate a high incidence of difficult tracheal intubation in children less than 60 weeks post-conceptual age commonly resulting in severe hypoxaemia. Reassuringly, the morbidity and mortality at 30 and 90 days was not increased by the occurrence of a difficult intubation event.
NCT02350348.
Mots-clé
Age Factors, Anesthesia/adverse effects, Anesthesia/mortality, Europe/epidemiology, Female, Humans, Hypoxia/diagnosis, Hypoxia/epidemiology, Hypoxia/mortality, Incidence, Infant, Infant, Newborn, Intubation, Intratracheal/adverse effects, Intubation, Intratracheal/mortality, Laryngoscopy/adverse effects, Laryngoscopy/mortality, Male, Medical Audit, Prospective Studies, Risk Assessment, Risk Factors, Severity of Illness Index, Time Factors, Treatment Outcome, airways, anaesthesia, difficult intubation, infants, morbidity, mortality, neonates, paediatric
Pubmed
Web of science
Open Access
Oui
Création de la notice
14/12/2022 17:06
Dernière modification de la notice
15/12/2022 7:51
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