Der akute Myokardinfarkt in der Schweiz: Resultate aus dem PIMICS-Herzinfarkt-Register. PIMICS-Projekt (Prospective Ischemia Myocardial Infarction Captopril Survey). [Acute myocardial infarct in Switzerland: results from the PIMICS Heart Infarct Register. PIMICS Project (Prospective Ischemia Myocardial Infarction Captopril Survey)]

Détails

ID Serval
serval:BIB_1CD49D41899C
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Titre
Der akute Myokardinfarkt in der Schweiz: Resultate aus dem PIMICS-Herzinfarkt-Register. PIMICS-Projekt (Prospective Ischemia Myocardial Infarction Captopril Survey). [Acute myocardial infarct in Switzerland: results from the PIMICS Heart Infarct Register. PIMICS Project (Prospective Ischemia Myocardial Infarction Captopril Survey)]
Périodique
Schweizerische Medizinische Wochenschrift
Auteur⸱e⸱s
Naegeli  B., Bertel  O., Urban  P., Angehrn  W., Siegrist  P., Stauffer  J. C., Baumann  P. C., Jolliet  P., Simeon-Dubach  D., Meier  B., Wunderlin  R.
ISSN
0036-7672 (Print)
Statut éditorial
Publié
Date de publication
05/1998
Volume
128
Numéro
19
Pages
729-36
Notes
English Abstract
Journal Article --- Old month value: May 9
Résumé
The aim of the PIMICS project was to create, for the first time in Switzerland, a registry of data concerning epidemiology and therapy in patients hospitalised for acute myocardial infarction covering all regions of the country. During 1995/96 73 Swiss hospitals of all categories took part in the PIMICS project. The ratio between males and females in the 3877 registered patients was 2.6:1 (2791 men vs. 1086 women). Female patients were significantly older than males (70.4 +/- 12.0 years vs. 63.4 +/- 12.6 years; p < 0.0001). The prevalence of risk factors differed between men and women: significantly more women had hypertension or diabetes, whereas smoking was more prevalent in males. The median delay between onset of symptoms and arrival at the hospital was 5.5 hours. Thrombolysis and primary angioplasty were more frequently performed in men (40.4% vs. 31.2% in women, p < 0.0001, and 5.7% in men vs. 3.5% in women, p = 0.005 respectively). During the acute phase males were treated more frequently with betablockers. The overall in-hospital mortality was 9.1%. It was significantly higher in female patients (13.5% vs. 7.4% in men; p < 0.0001) and in patients with reinfarction (14.5% vs. 7.1%; p < 0.0001). The mean hospital stay was 12.6 +/- 5.3 days. Only 7.7% of all patients with acute myocardial infarction were discharged within 6 days. At discharge, 51.7% were treated with betablockers and 69.3% with aspirin; 44.8% received ACE-inhibitors and only 13.8% lipid-lowering drugs. Follow-up measures such as coronary angiography and/or angioplasty or bypass surgery were performed significantly more often in males (45.0% vs. 32.9%; p < 0.0001). Likewise, men were more frequently assigned to a rehabilitation program than women (38.2% vs. 32.9%; p = 0.0004). The pre-hospital delay in patients with acute myocardial infarction remains too long. Primary and secondary prevention should be intensified in high risk groups, particularly in females. Thrombolysis and primary angioplasty as mainstays of treatment in acute myocardial infarction are generally used too sparingly, especially in women. With such measures the hospital stay could be shortened further.
Mots-clé
Adult Aged Captopril/therapeutic use Cross-Sectional Studies Female Hospital Mortality Humans Incidence Male Middle Aged Myocardial Infarction/drug therapy/*epidemiology/etiology Patient Admission/*statistics & numerical data Registries/*statistics & numerical data Switzerland/epidemiology Treatment Outcome
Pubmed
Web of science
Création de la notice
28/01/2008 10:29
Dernière modification de la notice
20/08/2019 12:53
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