Relationships between blood pressure components, lipids and lipoproteins in normotensive men

Détails

ID Serval
serval:BIB_1B6EC0D448A1
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Relationships between blood pressure components, lipids and lipoproteins in normotensive men
Périodique
Journal of Human Hypertension
Auteur(s)
Marques-Vidal P., Amar J., Cambou J.P., Chamontin B.
ISSN
0950-9240 (Print)
ISSN-L
0950-9240
Statut éditorial
Publié
Date de publication
1996
Peer-reviewed
Oui
Volume
10
Numéro
4
Pages
239-244
Langue
anglais
Notes
Publication types: Journal Article
Publication Status: ppublish
Résumé
The aim of this study is to assess the relationships between pulse pressure (PP) mean arterial pressure (MAP), clinical and lipid parameters in normotensive men. One hundred and twenty-seven normotensive men aged 35-64 years from the French department of Haute-Garonne were analysed. Blood pressure (BP) was measured using a random zero device. Correlation analysis was performed using Pearson's coefficient. Variables significantly related to PP and MAP were then introduced in a stepwise multiple regression analysis. On univariate analysis, PP was significantly and positively related to total cholesterol, triglycerides, VLDL and LDL-cholesterol and apo B. MAP was positively related to age, body mass index (BMI), triglycerides and VLDL-cholesterol. Stepwise multiple regression analysis showed only apo B to be independently related to PP after adjustment for MAP. Also, after adjustment for PP, only BMI and VLDL-cholesterol were related to MAP. Hence, MAP is related to BMI and VLDL-cholesterol, which are a common feature of hyperinsulinism. PP is linked to apo B, an important proatherogenic factor. These biological parameters appear specific of steady and pulsatile components of BP. The relationship between PP and apo B suggests a possible link between lipids and arterial stiffness, and may partly explain the prognostic value of PP in myocardial infarction.
Mots-clé
Lipids/blood, Lipoprotein(a)/blood, Lipoproteins/blood, Myocardial Infarction/physiopathology, Receptors, Angiotensin/analysis
Pubmed
Web of science
Création de la notice
01/12/2016 15:02
Dernière modification de la notice
20/08/2019 12:52
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