Prise en charge des troubles salivaires dans la sclérose latérale amyotrophique [Salivary management in amyotrophic lateral sclerosis]

Détails

ID Serval
serval:BIB_1AC528C4BB77
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Synthèse (review): revue aussi complète que possible des connaissances sur un sujet, rédigée à partir de l'analyse exhaustive des travaux publiés.
Collection
Publications
Institution
Titre
Prise en charge des troubles salivaires dans la sclérose latérale amyotrophique [Salivary management in amyotrophic lateral sclerosis]
Périodique
Revue medicale suisse
Auteur(s)
Fries S., Schweizer V.
ISSN
1660-9379 (Print)
ISSN-L
1660-9379
Statut éditorial
Publié
Date de publication
03/10/2018
Peer-reviewed
Oui
Volume
14
Numéro
621
Pages
1758-1762
Langue
français
Notes
Publication types: Journal Article
Publication Status: ppublish
Résumé
80 % of patients suffering from amyotrophic lateral sclerosis present bulbar involvement and 50 % have salivary symptoms, which are often poorly managed. They present either with drooling or thick secretions. This elevates the risk of bronchoaspiration leading to pneumonia, second cause of death in this population. It is hence paramount to treat, while enhancing the patient's quality of life. The first line of treatment is a salivary drying agent such as an atropine-based medication. These treatments have a low adverse effect rate, are reversible and easy to dose. Management of thick secretions is possible with mucolytics. Taking into account the severity of the bulbar involvement, the second line of treatment, once controversial, is salivary gland injections of botulinium toxin.
Mots-clé
Amyotrophic Lateral Sclerosis/complications, Humans, Quality of Life, Salivary Glands/physiopathology, Sialorrhea/etiology, Sialorrhea/therapy
Pubmed
Création de la notice
17/10/2018 10:45
Dernière modification de la notice
20/08/2019 12:51
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