Autism spectrum disorder in individuals with anorexia nervosa and in their first- and second-degree relatives: Danish nationwide register-based cohort-study.
Détails
ID Serval
serval:BIB_1AB9938B74C4
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Titre
Autism spectrum disorder in individuals with anorexia nervosa and in their first- and second-degree relatives: Danish nationwide register-based cohort-study.
Périodique
The British journal of psychiatry
ISSN
1472-1465 (Electronic)
ISSN-L
0007-1250
Statut éditorial
Publié
Date de publication
05/2015
Peer-reviewed
Oui
Volume
206
Numéro
5
Pages
401-407
Langue
anglais
Notes
Publication types: Journal Article ; Research Support, Non-U.S. Gov't
Publication Status: ppublish
Publication Status: ppublish
Résumé
Clinical and population-based studies report increased prevalence of autism spectrum disorders (ASD) in individuals with anorexia nervosa and in their relatives. No nationwide study has yet been published on co-occurrence of these disorders.
To investigate comorbidity of ASD in individuals with anorexia nervosa, and aggregation of ASD and anorexia nervosa in their relatives.
In Danish registers we identified all individuals born in 1981-2008, their parents, and full and half siblings, and linked them to data on hospital admissions for psychiatric disorders.
Risk of comorbidity of ASD in probands with anorexia nervosa and aggregation of ASD in families of anorexia nervosa probands were increased. However, the risk of comorbid and familial ASD did not differ significantly from comorbid and familial major depression or any psychiatric disorder in anorexia nervosa probands.
We confirm aggregation of ASD in probands with anorexia nervosa and in their relatives; however, the relationship between anorexia nervosa and ASD appears to be non-specific.
To investigate comorbidity of ASD in individuals with anorexia nervosa, and aggregation of ASD and anorexia nervosa in their relatives.
In Danish registers we identified all individuals born in 1981-2008, their parents, and full and half siblings, and linked them to data on hospital admissions for psychiatric disorders.
Risk of comorbidity of ASD in probands with anorexia nervosa and aggregation of ASD in families of anorexia nervosa probands were increased. However, the risk of comorbid and familial ASD did not differ significantly from comorbid and familial major depression or any psychiatric disorder in anorexia nervosa probands.
We confirm aggregation of ASD in probands with anorexia nervosa and in their relatives; however, the relationship between anorexia nervosa and ASD appears to be non-specific.
Mots-clé
Adolescent, Anorexia Nervosa/epidemiology, Autism Spectrum Disorder/epidemiology, Cohort Studies, Comorbidity, Denmark/epidemiology, Depressive Disorder, Major/epidemiology, Family/psychology, Female, Humans, Male, Regression Analysis, Risk Factors, Sex Distribution, Siblings/psychology
Pubmed
Open Access
Oui
Création de la notice
14/02/2019 10:13
Dernière modification de la notice
20/08/2019 13:51
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