During a 10-year period (January 1972 to December 1981), 69,066 fungal blood cultures were performed by using a biphasic brain heart infusion medium. A total of 838 fungi were recovered from 302 patients. Candida species represented 71% (595) of all positive cultures, Cryptococcus neoformans 12.6% (106), and Histoplasma capsulatum 13.1% (110).