T2-weighted spoiled gradient echo MRI for forensic age estimation: a study on knee growth plates.
Détails
ID Serval
serval:BIB_17DC16D0A9F9
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Titre
T2-weighted spoiled gradient echo MRI for forensic age estimation: a study on knee growth plates.
Périodique
International journal of legal medicine
ISSN
1437-1596 (Electronic)
ISSN-L
0937-9827
Statut éditorial
In Press
Peer-reviewed
Oui
Langue
anglais
Notes
Publication types: Journal Article
Publication Status: aheadofprint
Publication Status: aheadofprint
Résumé
The timing of growth plate fusion is a key indicator for age estimation and is primarily used in forensic investigations. On the other hand, non-ionizing techniques such as MRI are being developed to provide safer and more ethical evaluations in forensic casework. This study aims to evaluate the closure process of growth plates in the distal femoral and proximal tibial epiphyses using Multiple Echo Recombined Gradient Echo (MERGE) MRI sequences and provide age estimation data based on staging methods for forensic purposes. We retrospectively analyzed 559 patients (294 males, 265 females, aged 8-25 years) diagnosed with trauma and knee pain at Tepecik Training and Research Hospital from 2016 to 2019. MRI scans were performed using a 1.5-T system with MERGE sequences and evaluated by two observers using a new staging system. Observer agreement was assessed using Cohen's κ test, yielding high agreement values (κ > 0.8). Positive correlations were found between age and ossification stages (p < 0.001). Minimum age thresholds for stages 5a and 5b of the distal femoral epiphysis were 16 and 18 years for females and 17 and 19 years for males, respectively. For the proximal tibial epiphysis, the minimum ages for stages 5a and 5b were 15 years for females and 17 years for males. The MERGE sequence provides a viable method for assessing skeletal maturity in living individuals with significant ethical advantages due to non-ionizing radiation. This study supports the potential application of the MERGE sequence in forensic age estimation, demonstrating high observer agreement and consistency. Future research should focus on comparing different sequences and populations to enhance the methodology's applicability.
Mots-clé
Distal femoral epiphysis, Forensic age estimation, Growth plate closure, MERGE sequence, MRI, Proximal tibial epiphysis, Skeletal maturity
Pubmed
Web of science
Open Access
Oui
Création de la notice
25/10/2024 14:51
Dernière modification de la notice
02/11/2024 7:10