Full-term pregnancy with embryos from donated oocytes in a 36-year-old woman allografted for chronic myeloid leukemia

Détails

ID Serval
serval:BIB_17644C00AEDE
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Etude de cas (case report): rapporte une observation et la commente brièvement.
Collection
Publications
Titre
Full-term pregnancy with embryos from donated oocytes in a 36-year-old woman allografted for chronic myeloid leukemia
Périodique
Bone Marrow Transplantation
Auteur(s)
Rio  B., Letur-Konirsch  H., Ajchenbaum-Cymbalista  F., Bauduer  F., De Ziegler  D., Pelissier  C., Bernadou  A., Frydman  R., Zittoun  R.
ISSN
0268-3369
Statut éditorial
Publié
Date de publication
04/1994
Peer-reviewed
Oui
Volume
13
Numéro
4
Pages
487-8
Notes
Case Reports
Journal Article --- Old month value: Apr
Résumé
We report the first case of full-term pregnancy arising from donated oocytes in a 36-year-old woman with chronic myeloid leukemia (CML), 6 years after allogeneic bone marrow transplantation (BMT) following total body irradiation (TBI) (12 Gy) and cyclophosphamide 120 mg/kg. The first attempt at implantation with her own cryopreserved ovocytes was unsuccessful. Thereafter, she became pregnant after donated oocyte implantation using estradiol and progesterone support replacing the defective ovarian function. The baby was normal. Unfortunately, 6 months later, she relapsed in chronic phase of CML.
Mots-clé
Adult *Bone Marrow Transplantation Cyclophosphamide/administration & dosage *Embryo Transfer Estradiol/therapeutic use Female Humans Infant, Newborn Infertility, Female/etiology Leukemia, Myelogenous, Chronic, BCR-ABL Positive/*therapy Leukemia, Myeloid, Chronic-Phase/etiology *Oocytes Ovarian Failure, Premature/drug therapy/etiology Ovary/radiation effects Pregnancy *Pregnancy Outcome Progesterone/therapeutic use Radiation Injuries/etiology Tissue Donors Whole-Body Irradiation/adverse effects
Pubmed
Web of science
Création de la notice
28/02/2008 11:37
Dernière modification de la notice
20/08/2019 12:47
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