Optic perineuritis secondary to Wegener's granulomatosis.

Détails

ID Serval
serval:BIB_1663302D4E5D
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Etude de cas (case report): rapporte une observation et la commente brièvement.
Collection
Publications
Institution
Titre
Optic perineuritis secondary to Wegener's granulomatosis.
Périodique
Clinical experimental ophthalmology
Auteur(s)
Purvin V., Kawasaki A.
ISSN
1442-9071[electronic]
Statut éditorial
Publié
Date de publication
2009
Peer-reviewed
Oui
Volume
37
Numéro
7
Pages
712-7
Langue
anglais
Notes
Publication types: Case Reports ; Journal Article
Publication Status: ppublish
Résumé
BACKGROUND: Optic perineuritis (OPN) is an inflammatory condition involving the optic nerve sheath because of a variety of causes. We describe three patients in whom OPN was secondary to Wegener's granulomatosis (WG) and compare the clinical findings in these cases with those of idiopathic OPN. METHODS: This is a retrospective small case series derived from patients with OPN seen in an outpatient neuro-ophthalmology clinic. Medical records and imaging studies of these patients were reviewed. RESULTS: These patients shared clinical similarities with idiopathic OPN including age, sex, symptoms, radiographic findings and steroid responsiveness. However, recurrence of symptoms on lowering the prednisone dose below 40 mg distinguished these patients from those with idiopathic OPN. CONCLUSIONS: Steroid dependency in idiopathic OPN should raise suspicion of WG. Patients with OPN should be specifically questioned regarding pre-existing upper respiratory tract disorders and rheumatic symptoms and laboratory testing should include acute phase reactants, anti-neutrophil cytoplasmic antibodies and tests of renal function.
Mots-clé
Aged, Female, Glucocorticoids/therapeutic use, Humans, Magnetic Resonance Imaging, Male, Middle Aged, Optic Neuritis/diagnosis, Optic Neuritis/drug therapy, Orbit/pathology, Prednisone/therapeutic use, Retrospective Studies, Wegener Granulomatosis/complications, Wegener Granulomatosis/diagnosis
Pubmed
Web of science
Création de la notice
17/11/2009 15:15
Dernière modification de la notice
20/08/2019 13:45
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