Bacteremia due to viridans streptococci in neutropenic patients: a review

Détails

ID Serval
serval:BIB_164455F5AE46
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Synthèse (review): revue aussi complète que possible des connaissances sur un sujet, rédigée à partir de l'analyse exhaustive des travaux publiés.
Collection
Publications
Institution
Titre
Bacteremia due to viridans streptococci in neutropenic patients: a review
Périodique
American Journal of Medicine
Auteur(s)
Bochud  P. Y., Calandra  T., Francioli  P.
ISSN
0002-9343 (Print)
Statut éditorial
Publié
Date de publication
09/1994
Volume
97
Numéro
3
Pages
256-64
Notes
Journal Article Review --- Old month value: Sep
Résumé
Viridans streptococci have long been considered, with the exception of the ability to cause endocarditis, as minor pathogenic agents. More recently, however, these bacteria have become a major concern in neutropenic patients undergoing a chemotherapeutic treatment. In this high-risk population, they can be responsible for up to 39% of bacteremia cases and are the most frequent cause of this type of infection. The most frequently isolated species in blood cultures are Streptococcus mitis and Streptococcus sanguis II. Viridans streptococcus bacteremia can be accompanied by serious complications, like adult respiratory distress syndrome (ARDS) (3% to 33%), shock (7% to 18%) or endocarditis (7% to 8%). Mortality rates range from 6% to 30%. Case-control studies have identified the following risk factors: severe neutropenia (< 100 neutrophils/mm3), prophylactic antibiotic treatments with quinolone or co-trimoxazole, absence of intravenous antibiotics at the time of bacteremia, high doses of cytosine arabinoside, oropharyngeal mucositis, and heavy colonization by viridans streptococci. The introduction of penicillin in prophylactic antibiotic treatments has reduced the incidence of these infections, but the long-term use of penicillin could be compromised by the emergence of resistant strains.
Mots-clé
Bacteremia/epidemiology/*microbiology/prevention & control/therapy Humans Neutropenia/*complications Risk Factors Streptococcal Infections/epidemiology/*microbiology/prevention & control/therapy
Pubmed
Web of science
Création de la notice
25/01/2008 17:07
Dernière modification de la notice
20/08/2019 12:45
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