Granulomatous renal disease in a patient with common variable immunodeficiency

Détails

ID Serval
serval:BIB_15F6D9D7130C
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Titre
Granulomatous renal disease in a patient with common variable immunodeficiency
Périodique
Am J Kidney Dis
Auteur⸱e⸱s
Fakhouri F., Robino C., Lemaire M., Droz D., Noel L. H., Knebelmann B., Lesavre P.
ISSN
1523-6838 (Electronic)
ISSN-L
0272-6386
Statut éditorial
Publié
Date de publication
08/2001
Volume
38
Numéro
2
Pages
E7
Langue
anglais
Notes
Fakhouri, F
Robino, C
Lemaire, M
Droz, D
Noel, L H
Knebelmann, B
Lesavre, P
eng
Case Reports
Am J Kidney Dis. 2001 Aug;38(2):E7. doi: 10.1053/ajkd.2001.26117.
Résumé
Common variable immunodeficiency (CVID), the most common cause of primary hypogammaglobulinemia, is characterized by a decreased serum immunoglobulin level, recurrent infections, and the occurrence of various autoimmune diseases. Granulomatous disease has been reported previously in several patients with CVID, with granuloma occurring in the lymph nodes, spleen, liver, central nervous system, and bone marrow. We report the first published case of renal granulomatous disease in a CVID patient presenting with subacute renal failure. Renal function partially recovered after corticosteroid treatment and intravenous immunoglobulin infusions. The pathogenesis of granulomatous disease in CVID is unclear but may involve monocyte and T-cell abnormalities.
Mots-clé
Adult, Autoimmune Diseases/diagnosis/etiology, Biopsy, Common Variable Immunodeficiency/*complications, Female, Granuloma/diagnosis/*etiology, Humans, Kidney/pathology, Kidney Diseases/diagnosis/*etiology
Pubmed
Création de la notice
01/03/2022 11:18
Dernière modification de la notice
02/03/2022 7:35
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