Fluorescence of the bladder washout fluid following cystoscopy: a preliminary study

Détails

ID Serval
serval:BIB_150921075F66
Type
Actes de conférence (partie): contribution originale à la littérature scientifique, publiée à l'occasion de conférences scientifiques, dans un ouvrage de compte-rendu (proceedings), ou dans l'édition spéciale d'un journal reconnu (conference proceedings).
Sous-type
Abstract (résumé de présentation): article court qui reprend les éléments essentiels présentés à l'occasion d'une conférence scientifique dans un poster ou lors d'une intervention orale.
Collection
Publications
Institution
Titre
Fluorescence of the bladder washout fluid following cystoscopy: a preliminary study
Titre de la conférence
Conference on Photonic Therapeutics and Diagnostics VI
Auteur⸱e⸱s
Lovisa B., Novello A.M., Jichlinski P., Van den Bergh H., Wagnieres G.
Adresse
San Francisco, United-States, January 23-25, 2010
ISBN
0277-786X
Statut éditorial
Publié
Date de publication
2010
Volume
7548
Série
Proceedings of SPIE
Pages
75481J
Langue
anglais
Notes
Publication type : Proceedings Paper. Photonic Therapeutics and Diagnostics VI Book Series
Résumé
During fluorescence cystoscopy, it is observed that the acquired images are sometimes blurred by a greenish background originating from the bladder washout fluid. Several fluorophores are involved in this overall liquid fluorescence, and their exact origin and relative contributions remain unknown. In this study, the bladder washout fluid is sampled at different times during fluorescence cystoscopy examinations. In total, 32 samples from 12 patients are analyzed with a spectrofluorimeter (excitation range: 350-445 nm, emission range 380-700 nm). This study shows clearly that the position of the fluorescence peaks (excitation/emission wavelengths: 450/525 nm, 405/625 nm) and shoulder (440/525 nm) is reproducible between different patients. It also suggests that an excitation at wavelengths higher than 400 nm helps to suppress this solution background fluorescence. Additionally, the pH of the solution seems to influence the position of the fluorescence peaks, and this suggests that changing the pH of the examination liquid could help in avoiding the greenish background.
Mots-clé
urine, bladder cancer, fluorescence cystoscopy, PDD, photoactive porphyrins, 4-PYRIDOXIC ACID, HUMAN-URINE, CANCER, PH
Création de la notice
28/12/2011 11:15
Dernière modification de la notice
20/08/2019 13:44
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