MiR-210: A potential therapeutic target against radiation-induced enteropathy.

Détails

ID Serval
serval:BIB_13C211EFA686
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Titre
MiR-210: A potential therapeutic target against radiation-induced enteropathy.
Périodique
Radiotherapy and oncology
Auteur(s)
Hamama S., Noman M.Z., Gervaz P., Delanian S., Vozenin M.C.
ISSN
1879-0887 (Electronic)
ISSN-L
0167-8140
Statut éditorial
Publié
Date de publication
05/2014
Peer-reviewed
Oui
Volume
111
Numéro
2
Pages
219-221
Langue
anglais
Notes
Publication types: Journal Article
Publication Status: ppublish
Résumé
A previously undescribed and robust miR210 overexpression is shown in intestinal samples obtained from patients with radiation enteropathy and fibrotic cultured cells. In addition, miR-210 overexpression is repressed by antifibrotic treatment combining pentoxifylline and α-tocopherol.

Mots-clé
Antioxidants/therapeutic use, Cells, Cultured/drug effects, Cells, Cultured/metabolism, Drug Therapy, Combination, Fibrosis/drug therapy, Fibrosis/metabolism, Humans, Hypoxia/metabolism, Intestinal Diseases/drug therapy, Intestinal Diseases/metabolism, MicroRNAs/antagonists & inhibitors, MicroRNAs/metabolism, Molecular Targeted Therapy/methods, Myocytes, Smooth Muscle/drug effects, Myocytes, Smooth Muscle/metabolism, Pentoxifylline/therapeutic use, Platelet Aggregation Inhibitors/therapeutic use, RNA/metabolism, Radiation Injuries/drug therapy, Radiation Injuries/metabolism, Radiation-Protective Agents/therapeutic use, Radiotherapy/adverse effects, alpha-Tocopherol/therapeutic use, Anti-fibrotic treatment, Pentoxifylline, Radiation enteropathy, Radiation-induced fibrosis, Trolox, microRNA miR-210
Pubmed
Web of science
Création de la notice
17/04/2018 10:09
Dernière modification de la notice
20/08/2019 13:42
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