Satellite PET and lung cancer: a prospective study in surgical patients.

Détails

ID Serval
serval:BIB_13A2B4204E81
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Satellite PET and lung cancer: a prospective study in surgical patients.
Périodique
Nuclear Medicine Communications
Auteur⸱e⸱s
Slosman D.O., Spiliopoulos A., Couson F., Nicod L., Louis O., Lemoine R., Donath A., Junod A.F.
ISSN
0143-3636[print], 0143-3636[linking]
Statut éditorial
Publié
Date de publication
1993
Volume
14
Numéro
11
Pages
955-961
Langue
anglais
Résumé
Positron emission tomography (PET) appears to be an innovative method for imaging the proliferative activity of malignant tissue, in particular by means of 18F-labelled fluorodeoxyglucose (FDG). The potential role of PET scanning was investigated in a satellite centre as an adjunct to conventional methods for estimating the likelihood of pulmonary malignancy. Therefore the sensitivity of detection of lung cancer in candidates was determined prior to exploratory or therapeutic thoracotomy by FDG PET imaging. The study involved 36 patients with abnormal chest roentgenogram and suspected lung cancer who were due for thoracotomy. The PET scans were evaluated qualitatively and semiquantitatively. Pulmonary malignancy was found in 31/36 patients and 29 had a focal increase in FDG pulmonary uptake. Benign pulmonary lesions were found in 5/36 patients, three of whom had a negative PET scan. The sensitivity of detection of lung cancer by FDG PET was therefore 93.5%. Bayesian study shows that FDG PET could be the most useful method in a population with a low prevalence of lung cancer. As illustrated by our study, a simple FDG PET scanning protocol in a satellite PET centre could provide adequate clinical information and help in deciding subsequent patient management.
Mots-clé
Adenocarcinoma/radionuclide imaging, Adenocarcinoma/surgery, Adult, Aged, Carcinoma, Squamous Cell/radionuclide imaging, Carcinoma, Squamous Cell/surgery, Deoxyglucose/analogs & derivatives, Deoxyglucose/diagnostic use, Female, Fluorodeoxyglucose F18, Hospitals, Satellite, Humans, Lung Neoplasms/radionuclide imaging, Lung Neoplasms/surgery, Male, Middle Aged, Prospective Studies, Sensitivity and Specificity, Tomography, Emission-Computed
Pubmed
Web of science
Création de la notice
19/02/2010 19:13
Dernière modification de la notice
20/08/2019 13:42
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