Cushing's syndrome in an 81-year-old patient treated with budesonide and amiodarone

Détails

ID Serval
serval:BIB_132F375B9B47
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Etude de cas (case report): rapporte une observation et la commente brièvement.
Collection
Publications
Institution
Titre
Cushing's syndrome in an 81-year-old patient treated with budesonide and amiodarone
Périodique
European Journal of Gastroenterology and Hepatology
Auteur(s)
Ahle  G. B., Blum  A. L., Martinek  J., Oneta  C. M., Dorta  G.
ISSN
0954-691X (Print)
Statut éditorial
Publié
Date de publication
09/2000
Volume
12
Numéro
9
Pages
1041-2
Notes
Case Reports
Journal Article --- Old month value: Sep
Résumé
This is the first report of Cushing's syndrome under oral budesonide treatment. An 81-year-old man known for paroxysmal atrial fibrillation and chronic renal insufficiency, treated with 6 mg budesonide for collagenous colitis, developed Cushing's syndrome under co-administration of amiodarone. The Cushing's syndrome disappeared after discontinuation of the amiodarone treatment. Metabolism of the two medications by hepatic cytochrome P 450 3A may explain the development of Cushing's syndrome.
Mots-clé
Aged Aged, 80 and over Amiodarone/therapeutic use Anti-Arrhythmia Agents/therapeutic use Anti-Inflammatory Agents/*adverse effects/therapeutic use Atrial Fibrillation/drug therapy Budesonide/*adverse effects/therapeutic use Cushing Syndrome/*chemically induced Cytochrome P-450 Enzyme System/metabolism Humans Male
Pubmed
Web of science
Création de la notice
25/01/2008 15:48
Dernière modification de la notice
20/08/2019 12:41
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