Effects of salbutamol and caffeine ingestion on exercise metabolism and performance

Détails

ID Serval
serval:BIB_12E416132C41
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Effects of salbutamol and caffeine ingestion on exercise metabolism and performance
Périodique
International Journal of Sports Medicine
Auteur(s)
Collomp K., Candau R., Millet G., Mucci P., Borrani F., Préfaut C., De Ceaurriz J.
ISSN
0172-4622
Statut éditorial
Publié
Date de publication
11/2002
Peer-reviewed
Oui
Volume
23
Numéro
8
Pages
549-554
Langue
anglais
Notes
Publication types: Clinical Trial ; Comparative Study ; Journal Article ; Randomized Controlled Trial Publication Status: ppublish
Résumé
This study was designed to assess the effects of acute oral salbutamol and caffeine intake on performance and metabolism during short-term endurance exercise. Eight healthy volunteers participated in the double-blind placebo-controlled randomized cross-over study. Two 10 min cycling trials were performed at a power corresponding to 90 % VO 2 max for the first and a mock test for the second, separated by 10 min of passive recovery after ingestion of placebo (Pla), salbutamol (Sal, 6 mg) and caffeine (Caf, 250 mg). Performance (mean power during the mock test) was not statistically significant between the 3 treatments. Blood lactate was significantly increased after Sal compared to Pla at rest and until the end of the mock test whereas it appeared significantly increased after Caf compared to Pla at the end of the two exercises. Sal increased basal blood glucose and both Sal and Caf induced significant higher plasma insulin concentrations at rest, at the end of the mock test and during the recovery compared to Pla. No significant changes were found in these three variables between the Sal and the Caf treatments. Plasma growth hormone was significantly decreased after Sal after the mock test compared to the two other treatments. In conclusion, under the conditions of this study, neither oral salbutamol nor caffeine intake produce enhancement of short-term performance in non-specific trained subjects despite the substantial shifts in metabolic and hormonal parameters which were found.
Mots-clé
Administration, Oral, Adult, Albuterol/pharmacology, Blood Glucose/drug effects, Caffeine/pharmacology, Cross-Over Studies, Double-Blind Method, Energy Metabolism/drug effects, Exercise/physiology, Growth Hormone/blood, Humans, Insulin/blood, Lactic Acid/blood, Male, Task Performance and Analysis
Pubmed
Web of science
Création de la notice
25/09/2008 9:01
Dernière modification de la notice
20/08/2019 13:41
Données d'usage