A pooled analysis of case-control studies of thyroid cancer. II. Menstrual and reproductive factors.

Détails

ID Serval
serval:BIB_11557
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Titre
A pooled analysis of case-control studies of thyroid cancer. II. Menstrual and reproductive factors.
Périodique
Cancer causes & control
Auteur⸱e⸱s
Negri E., Dal Maso L., Ron E., La Vecchia C., Mark S.D., Preston-Martin S., McTiernan A., Kolonel L., Yoshimoto Y., Jin F., Wingren G., Rosaria Galanti M., Hardell L., Glattre E., Lund E., Levi F., Linos D., Braga C., Franceschi S.
ISSN
0957-5243 (Print)
ISSN-L
0957-5243
Statut éditorial
Publié
Date de publication
04/1999
Peer-reviewed
Oui
Volume
10
Numéro
2
Pages
143-155
Langue
anglais
Notes
Publication types: Journal Article ; Meta-Analysis ; Research Support, Non-U.S. Gov't ; Research Support, U.S. Gov't, P.H.S.
Publication Status: ppublish
Résumé
It has been suggested that female hormones, and hence menstrual and reproductive factors, play a role in thyroid cancer etiology. Epidemiological data, however, are limited and inconsistent, partly because of the small number of cases included in each study. To clarify the etiology of thyroid cancer, we conducted a pooled analysis of original data from 14 case-control studies, 4 from the United States, 2 from Asia, and 8 from Europe.
This analysis included a total of 2,247 female cases of thyroid cancer (80% papillary) and 3,699 control women. Pooled odds ratios (OR) were estimated using logistic regression, conditioning on study and (i) matching sets for individually matched studies, or (ii) quinquennia of age for the other studies. Additional terms for age and history of radiation exposure were included in the regression equations.
The OR per year of later menarche was 1.04 (95% confidence interval (CI) 1.0-1.1). Compared to premenopausal women, the OR was 1.3 for women with natural menopause, and 1.8 for those with artificial menopause, but the studies were heterogeneous and the association may be due, at least in part, to diagnostic or ascertainment bias. Parity, spontaneous or induced abortions and history of infertility were not associated with thyroid cancer risk. The OR was above unity in women reporting later age at first birth (OR = 1.1, 95% CI 1.0-1.3 for 5-year delay) and higher in the first years after a birth.
The associations of menstrual and reproductive factors with thyroid cancer risk were generally weak, but appeared stronger among women diagnosed with thyroid cancer at younger ages.
Mots-clé
Adenocarcinoma, Papillary/epidemiology, Adenocarcinoma, Papillary/etiology, Adenocarcinoma, Papillary/pathology, Adolescent, Adult, Age Distribution, Aged, Asia/epidemiology, Case-Control Studies, Confidence Intervals, Europe/epidemiology, Female, Humans, Logistic Models, Menarche/physiology, Menopause/physiology, Middle Aged, Odds Ratio, Parity/physiology, Pregnancy, Risk Assessment, Risk Factors, Thyroid Neoplasms/epidemiology, Thyroid Neoplasms/etiology, Thyroid Neoplasms/pathology, United States/epidemiology
Pubmed
Web of science
Création de la notice
19/11/2007 12:02
Dernière modification de la notice
15/04/2023 5:51
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