Bench-to-bedside review: contrast enhanced ultrasonography--a promising technique to assess renal perfusion in the ICU.

Détails

ID Serval
serval:BIB_114850F90873
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Synthèse (review): revue aussi complète que possible des connaissances sur un sujet, rédigée à partir de l'analyse exhaustive des travaux publiés.
Collection
Publications
Titre
Bench-to-bedside review: contrast enhanced ultrasonography--a promising technique to assess renal perfusion in the ICU.
Périodique
Critical Care (london, England)
Auteur⸱e⸱s
Schneider A., Johnson L., Goodwin M., Schelleman A., Bellomo R.
ISSN
1466-609X (Electronic)
ISSN-L
1364-8535
Statut éditorial
Publié
Date de publication
2011
Peer-reviewed
Oui
Volume
15
Numéro
3
Pages
157
Langue
anglais
Notes
Publication types: Journal Article ; Review Publication Status: ppublish
Résumé
Acute kidney injury (AKI) is common in critically ill patients and associated with important morbidity and mortality. Although alterations in renal perfusion are thought to play a causative role in the pathogenesis of AKI, there is, to date, no reliable technique that allows the assessment of renal perfusion that is applicable in the ICU. Contrast-enhanced ultrasound (CEUS) is an ultrasound imaging technique that makes use of microbubble-based contrast agents. These microbubbles, when injected into the bloodstream, allow visualization of vascular structures and, with contrast-specific imaging modes, detection of blood flow at the capillary level. Some recent CEUS-derived approaches allow quantification of blood flow in several organs, including the kidney. Current generation ultrasound contrast agents have strong stability and safety profiles. Along with post-marketing surveillance, numerous studies report safe administration of these agents, including in critically ill patients. This review presents information on the physical principles underlying CEUS, the methods allowing blood flow quantification and the potential applications of CEUS in critical care nephrology, currently as a research tool but perhaps in the future as a way of monitoring renal perfusion.
Mots-clé
Acute Kidney Injury/physiopathology, Acute Kidney Injury/ultrasonography, Animals, Contrast Media/diagnostic use, Humans, Intensive Care Units/trends, Kidney/blood supply, Kidney/ultrasonography, Microbubbles/diagnostic use, Point-of-Care Systems/trends
Pubmed
Web of science
Open Access
Oui
Création de la notice
26/11/2014 21:22
Dernière modification de la notice
20/08/2019 12:38
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