Epistasis and maternal effects in experimental adaptation to chronic nutritional stress in Drosophila.

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Etat: Public
Version: de l'auteur
ID Serval
serval:BIB_113A967A93EB
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Titre
Epistasis and maternal effects in experimental adaptation to chronic nutritional stress in Drosophila.
Périodique
Journal of Evolutionary Biology
Auteur(s)
Vijendravarma R.K., Kawecki T.J.
ISSN
1420-9101 (Electronic)
ISSN-L
1010-061X
Statut éditorial
Publié
Date de publication
2013
Peer-reviewed
Oui
Volume
26
Numéro
12
Pages
2566-2580
Langue
anglais
Résumé
Based on ecological and metabolic arguments, some authors predict that adaptation to novel, harsh environments should involve alleles showing negative (diminishing return) epistasis and/or that it should be mediated in part by evolution of maternal effects. Although the first prediction has been supported in microbes, there has been little experimental support for either prediction in multicellular eukaryotes. Here we use a line-cross design to study the genetic architecture of adaptation to chronic larval malnutrition in a population of Drosophila melanogaster that evolved on an extremely nutrient-poor larval food for 84 generations. We assayed three fitness-related traits (developmental rate, adult female weight and egg-to-adult viability) under the malnutrition conditions in 14 crosses between this selected population and a nonadapted control population originally derived from the same base population. All traits showed a pattern of negative epistasis between alleles improving performance under malnutrition. Furthermore, evolutionary changes in maternal traits accounted for half of the 68% increase in viability and for the whole of 8% reduction in adult female body weight in the selected population (relative to unselected controls). These results thus support both of the above predictions and point to the importance of nonadditive effects in adaptive microevolution.
Mots-clé
epistasis, experimental evolution, genetic architecture, line-cross analysis, malnutrition, maternal effect
Pubmed
Web of science
Création de la notice
19/08/2013 10:09
Dernière modification de la notice
20/08/2019 12:38
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