Effect of Pre-Hospital Intubation in Patients with Severe Traumatic Brain Injury on Outcome: A Prospective Cohort Study.

Détails

Ressource 1Télécharger: jcm-08-00470 (1).pdf (624.38 [Ko])
Etat: Public
Version: Final published version
Licence: CC BY 4.0
ID Serval
serval:BIB_11146EF99DE8
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Titre
Effect of Pre-Hospital Intubation in Patients with Severe Traumatic Brain Injury on Outcome: A Prospective Cohort Study.
Périodique
Journal of clinical medicine
Auteur(s)
Choffat C., Delhumeau C., Fournier N., Schoettker P.
ISSN
2077-0383 (Print)
ISSN-L
2077-0383
Statut éditorial
Publié
Date de publication
06/04/2019
Peer-reviewed
Oui
Volume
8
Numéro
4
Langue
anglais
Notes
Publication types: Journal Article
Publication Status: epublish
Résumé
Secondary injuries are associated with bad outcomes in the case of severe traumatic brain injury (sTBI). Patients with a Glasgow Coma Scale (GCS) < 9 should undergo pre-hospital intubation (PHI). There is controversy about whether PHI is beneficial. The aim of this study was to estimate the effect of PHI in patients after sTBI. A multicenter, prospective cohort study was performed in Switzerland, including 832 adults with sTBI. Outcomes were death and impaired consciousness at 14 days. Associations between risk factors and outcomes were assessed with univariate and multivariate Cox models for survival, and univariate and multivariate regression models for impaired consciousness. Potential risk factors were age, GCS on scene, pupil reaction, Injury Severity Score (ISS), PHI, oxygen administration, and type of admission to trauma center. Age, GCS on scene < 9, abnormal pupil reaction and ISS ≥ 25 were associated with mortality. GCS < 9 and ISS ≥ 25 were correlated with impaired consciousness. PHI was overall not associated with short-term mortality and consciousness. However, there was a significative interaction with PHI and major trauma. PHI improves outcome from patients with sTBI and an ISS ≥ 25.
Mots-clé
neurotrauma, pre-hospital intubation, secondary injury, severe traumatic brain injury
Pubmed
Open Access
Oui
Création de la notice
15/04/2019 18:19
Dernière modification de la notice
13/12/2019 8:08
Données d'usage