Outcome of mechanical ventilation for acute respiratory failure in patients with pulmonary fibrosis.

Détails

ID Serval
serval:BIB_109986D950BE
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Outcome of mechanical ventilation for acute respiratory failure in patients with pulmonary fibrosis.
Périodique
Intensive Care Medicine
Auteur(s)
Fumeaux T., Rothmeier C., Jolliet P.
ISSN
0342-4642 (Print)
ISSN-L
0342-4642
Statut éditorial
Publié
Date de publication
2001
Peer-reviewed
Oui
Volume
27
Numéro
12
Pages
1868-1874
Langue
anglais
Notes
Publication types: Journal ArticlePublication Status: ppublish
Résumé
OBJECTIVE: During the course of idiopathic pulmonary fibrosis patients may need invasive mechanical ventilation because of acute respiratory failure. We reviewed the charts of all patients with idiopathic pulmonary fibrosis admitted to our ICU for mechanical ventilation to describe their ICU course and prognosis.
DESIGN AND SETTING: Retrospective, observational case series, from December 1996 to March 2001, in an 18-bed medical ICU in a tertiary university hospital.
PATIENTS: Fourteen consecutive patients with idiopathic ( n=11) or secondary ( n=3) pulmonary fibrosis admitted to the medical ICU for mechanical ventilation.
MEASUREMENTS AND RESULTS: Relevant factors of history and hospital course such as diagnostic and therapeutic interventions were retrieved as well as laboratory and radiological results. All patients were admitted for severe acute hypoxemic respiratory failure (PaO(2)/FIO(2) 111+/-64 mmHg), with a high clinical suspicion of lower respiratory tract infection. Despite ventilatory support and adjunctive therapies (antibiotics, steroids, or immunosuppressive drugs), all patients gradually worsened and eventually died in the ICU after a mean stay of 7.6+/-4.6 days.
CONCLUSIONS: In this study mechanical ventilation for acute respiratory failure in pulmonary fibrosis patients was associated with a 100% mortality, despite aggressive therapeutic and diagnostic procedures.
Mots-clé
Acute Disease, Aged, Aged, 80 and over, Female, Humans, Intensive Care Units, Male, Middle Aged, Pulmonary Fibrosis/mortality, Pulmonary Fibrosis/therapy, Respiration, Artificial, Respiratory Insufficiency/mortality, Respiratory Insufficiency/therapy, Retrospective Studies, Survival Rate, Switzerland/epidemiology, Treatment Outcome
Pubmed
Web of science
Création de la notice
27/06/2013 14:51
Dernière modification de la notice
20/08/2019 12:37
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