This article is an introduction to a special issue on ‘Contexts of Religious Tolerance: New Perspectives from Early Modern Britain and Beyond’, which contains essays on the contributions to the debates on tolerance by non-canonical philosophers and theologians, mainly from seventeenth- and eighteenth-century Scotland and England. Among the studied authors are the Aberdeen Doctors, Samuel Rutherford, James Dundas, John Finch, George Keith, John Simson, Archibald Campbell, Francis Hutcheson, George Turnbull and John Witherspoon. The introduction draws attention to several methodological points connected to the decision to look at the debates on tolerance through the prism of rarely studied authors. It then presents the essays, which offer novel perspectives by analysing and contextualising political, religious and moral treatments of tolerance. These are tied especially to debates on the articles of faith and on their status, on confessions of faith and their role in the quest for orthodoxy, on liberty of conscience, and on the relation between church and state.