Fulminant hepatic and multiple organ failure following acute viral tonsillitis: a case report.

Détails

ID Serval
serval:BIB_0D44119EC3B3
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Etude de cas (case report): rapporte une observation et la commente brièvement.
Collection
Publications
Titre
Fulminant hepatic and multiple organ failure following acute viral tonsillitis: a case report.
Périodique
Journal of medical case reports
Auteur⸱e⸱s
Bechtel-Grosch U., Beguelin C., Berezowska S., Dufour J.F., Takala J., Schefold J.C.
ISSN
1752-1947 (Electronic)
ISSN-L
1752-1947
Statut éditorial
Publié
Date de publication
20/01/2016
Peer-reviewed
Oui
Volume
10
Pages
7
Langue
anglais
Notes
Publication types: Case Reports ; Journal Article
Publication Status: epublish
Résumé
Pyogenic tonsillitis may often be observed in the general Western population. In severe cases, it may require antibiotic treatment or even hospitalization and often a prompt clinical response will be noted. Here we present an unusual case of progressive multiple organ failure including fulminant liver failure following acute tonsillitis initially mistaken for "classic" pyogenic (that is bacterial) tonsillitis.
A 68-year-old previously healthy white man was referred with suspicion of pyogenic angina. After tonsillectomy, he developed acute liver failure and consecutive multiple organ failure including acute hemodynamic, pulmonary and dialysis-dependent renal failure. Immunohistopathological analysis of his tonsils and liver as well as serum polymerase chain reaction analyses revealed herpes simplex virus-2 to be the causative pathogen. Treatment included high-dose acyclovir and multiorgan supportive intensive care therapy. His final outcome was favorable.
Fulminant herpes simplex virus-2-induced multiple organ failure is rarely observed in the Western hemisphere and should be considered a potential diagnosis in patients with tonsillitis and multiple organ failure including acute liver failure. From a clinical perspective, it seems important to note that fulminant herpes simplex virus-2 infection may masquerade as "routine" bacterial severe sepsis/septic shock. This persevering condition should be diagnosed early and treated goal-oriented in order to gain control of this life-threatening condition.
Mots-clé
Acute Disease, Acyclovir/therapeutic use, Aged, Antiviral Agents/therapeutic use, Critical Care, Herpes Simplex/complications, Herpes Simplex/drug therapy, Herpes Simplex/physiopathology, Herpesvirus 2, Human/isolation & purification, Humans, Liver/virology, Liver Failure, Acute/drug therapy, Liver Failure, Acute/virology, Male, Multiple Organ Failure/drug therapy, Multiple Organ Failure/virology, Tonsillitis/complications, Tonsillitis/surgery, Tonsillitis/virology, Treatment Outcome
Pubmed
Open Access
Oui
Création de la notice
29/06/2020 12:54
Dernière modification de la notice
30/06/2020 6:26
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