Sleep deprivation in narcoleptic subjects: effect on sleep stages and EEG power density.

Détails

ID Serval
serval:BIB_0D33C8B2F8A3
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Sleep deprivation in narcoleptic subjects: effect on sleep stages and EEG power density.
Périodique
Electroencephalography and Clinical Neurophysiology
Auteur(s)
Tafti M., Rondouin G., Besset A., Billiard M.
ISSN
0013-4694[print], 0013-4694[linking]
Statut éditorial
Publié
Date de publication
12/1992
Volume
83
Numéro
6
Pages
339-349
Langue
anglais
Notes
Publication types: Clinical Trial ; Journal Article ; Research Support, Non-U.S. Gov't
Publication Status: ppublish
Résumé
Sleep of 8 narcoleptic and 8 control subjects was recorded under baseline (i.e., prior wakefulness 16 h) and after 24 h without sleep. During both baseline and recovery total sleep time and stage 2 non-REM sleep were significantly decreased in narcoleptic subjects. Slow wave activity (i.e., EEG power density in the range of 0.75-4.5 Hz) decayed exponentially during baseline and after sleep deprivation in both narcoleptic and control subjects. During both baseline and recovery EEG power density in delta and sigma frequencies in non-REM sleep was enhanced in narcoleptic subjects relative to controls. In REM sleep differences in the same direction were present in delta and beta frequencies. After sleep deprivation EEG power density in non-REM sleep was elevated in delta and some higher frequencies in both patients and controls, but the response to sleep deprivation was stronger in narcoleptic subjects. These data show that in narcoleptic subjects regulatory processes underlying non-REM sleep homeostasis are operative and indicate that the response to sleep deprivation is stronger than in control subjects.
Mots-clé
Adolescent, Adult, Electroencephalography, Female, Humans, Male, Narcolepsy/physiopathology, Sleep Deprivation/physiology, Sleep Stages/physiology
Pubmed
Web of science
Création de la notice
24/01/2008 16:55
Dernière modification de la notice
20/08/2019 13:34
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