Primate adult brain cell autotransplantation, a new tool for brain repair?
Détails
ID Serval
serval:BIB_0C3BF5C7AC3F
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Titre
Primate adult brain cell autotransplantation, a new tool for brain repair?
Périodique
Experimental Neurology
ISSN
0014-4886
Statut éditorial
Publié
Date de publication
11/2005
Peer-reviewed
Oui
Volume
196
Numéro
1
Pages
195-8
Notes
Journal Article
Research Support, Non-U.S. Gov't --- Old month value: Nov
Research Support, Non-U.S. Gov't --- Old month value: Nov
Résumé
If successful, autologous brain cell transplantation is an attractive approach to repair lesions and restore function of the central nervous system. We demonstrate that monkey adult brain cells obtained from cortical biopsy and kept in culture for 4 weeks exhibit neural progenitor characteristics. After reimplantation into a lesion area of the donor cerebral cortex, these cells can successfully survive and acquire neuronal characteristics over time. These results open new perspectives in the field of brain repair and may lead to future clinical applications.
Mots-clé
Animals
Brain Injuries/*therapy
Brain Tissue Transplantation/*methods
Cell Culture Techniques
Cells, Cultured
Disease Models, Animal
Immunohistochemistry
Microscopy, Confocal
Neurons/*cytology/*transplantation
Primates
Transplantation, Autologous
Pubmed
Web of science
Création de la notice
06/02/2008 10:44
Dernière modification de la notice
20/08/2019 13:33