Primate adult brain cell autotransplantation, a new tool for brain repair?

Détails

ID Serval
serval:BIB_0C3BF5C7AC3F
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Titre
Primate adult brain cell autotransplantation, a new tool for brain repair?
Périodique
Experimental Neurology
Auteur(s)
Brunet  J. F., Rouiller  E., Wannier  T., Villemure  J. G., Bloch  J.
ISSN
0014-4886
Statut éditorial
Publié
Date de publication
11/2005
Peer-reviewed
Oui
Volume
196
Numéro
1
Pages
195-8
Notes
Journal Article
Research Support, Non-U.S. Gov't --- Old month value: Nov
Résumé
If successful, autologous brain cell transplantation is an attractive approach to repair lesions and restore function of the central nervous system. We demonstrate that monkey adult brain cells obtained from cortical biopsy and kept in culture for 4 weeks exhibit neural progenitor characteristics. After reimplantation into a lesion area of the donor cerebral cortex, these cells can successfully survive and acquire neuronal characteristics over time. These results open new perspectives in the field of brain repair and may lead to future clinical applications.
Mots-clé
Animals Brain Injuries/*therapy Brain Tissue Transplantation/*methods Cell Culture Techniques Cells, Cultured Disease Models, Animal Immunohistochemistry Microscopy, Confocal Neurons/*cytology/*transplantation Primates Transplantation, Autologous
Pubmed
Web of science
Création de la notice
06/02/2008 9:44
Dernière modification de la notice
20/08/2019 12:33
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