Transcriptomic analyses of murine ventricular cardiomyocytes.

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Ressource 1Télécharger: sdata2018170.pdf (1330.09 [Ko])
Etat: Public
Version: Final published version
ID Serval
serval:BIB_0C3727C1173F
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Titre
Transcriptomic analyses of murine ventricular cardiomyocytes.
Périodique
Scientific Data
Auteur(s)
Chevalier M., Vermij S.H., Wyler K., Gillet L., Keller I., Abriel H.
ISSN
2052-4463 (Electronic)
ISSN-L
2052-4463
Statut éditorial
Publié
Date de publication
2018
Peer-reviewed
Oui
Volume
5
Pages
180170
Langue
anglais
Résumé
Mice are used universally as model organisms for studying heart physiology, and a plethora of genetically modified mouse models exist to study cardiac disease. Transcriptomic data for whole-heart tissue are available, but not yet for isolated ventricular cardiomyocytes. Our lab therefore collected comprehensive RNA-seq data from wildtype murine ventricular cardiomyocytes as well as from knockout models of the ion channel regulators CASK, dystrophin, and SAP97. We also elucidate ion channel expression from wild-type cells to help forward the debate about which ion channels are expressed in cardiomyocytes. Researchers studying the heart, and especially cardiac arrhythmias, may benefit from these cardiomyocyte-specific transcriptomic data to assess expression of genes of interest.
Pubmed
Web of science
Open Access
Oui
Création de la notice
29/08/2018 15:05
Dernière modification de la notice
20/08/2019 12:33
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