Complications of regional citrate anticoagulation: accumulation or overload?
Détails
Etat: Public
Version: Final published version
Licence: CC BY 4.0
ID Serval
serval:BIB_0BC657CF48C8
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Synthèse (review): revue aussi complète que possible des connaissances sur un sujet, rédigée à partir de l'analyse exhaustive des travaux publiés.
Collection
Publications
Institution
Titre
Complications of regional citrate anticoagulation: accumulation or overload?
Périodique
Critical care
ISSN
1466-609X (Electronic)
ISSN-L
1364-8535
Statut éditorial
Publié
Date de publication
19/11/2017
Peer-reviewed
Oui
Volume
21
Numéro
1
Pages
281
Langue
anglais
Notes
Publication types: Journal Article
Publication Status: epublish
Publication Status: epublish
Résumé
Regional citrate anticoagulation (RCA) is now recommended over systemic heparin for continuous renal replacement therapy in patients without contraindications. Its use is likely to increase throughout the world. However, in the absence of citrate blood level monitoring, the diagnosis of citrate accumulation, the most feared complication of RCA, remains relatively complex. It is therefore commonly mistaken with other conditions. This review aims at providing clarifications on RCA-associated acid-base disturbances and their management at the bedside. In particular, the authors wish to propose a clear distinction between citrate accumulation and net citrate overload.
Mots-clé
Acid-Base Equilibrium/physiology, Acute Kidney Injury/drug therapy, Anticoagulants/adverse effects, Anticoagulants/therapeutic use, Citric Acid/adverse effects, Citric Acid/analysis, Citric Acid/therapeutic use, Humans, Intensive Care Units/organization & administration, Renal Replacement Therapy/instrumentation, Renal Replacement Therapy/methods, Renal Replacement Therapy/trends, Acute kidney injury, Citrate accumulation, Complications of therapy, Continuous renal replacement therapy, Metabolic alkalosis, Regional citrate anticoagulation
Pubmed
Web of science
Open Access
Oui
Création de la notice
23/11/2017 21:49
Dernière modification de la notice
20/08/2019 13:33