Perforation or uncontrollable hemorrhage following a stress ulcer rarely occurs in high risk children if strict prophylactic measures are adopted. However, we have observed and operated 3 cases over a period of 2 years. Despite the diverse etiologies and contrary to some authors, we have always chosen the simplest and least mutilating operation in order to preserve the physiologic function of the digestive tract. The aim of this article is to compare our therapeutic attitude with that of the literature.