Organization of the projections from barrel cortex to thalamus in mice studied with Phaseolus vulgaris-leucoagglutinin and HRP

Détails

ID Serval
serval:BIB_0B069D7C6BA5
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Titre
Organization of the projections from barrel cortex to thalamus in mice studied with Phaseolus vulgaris-leucoagglutinin and HRP
Périodique
Experimental Brain Research
Auteur(s)
Hoogland  P. V., Welker  E., Van der Loos  H.
ISSN
0014-4819 (Print)
Statut éditorial
Publié
Date de publication
1987
Volume
68
Numéro
1
Pages
73-87
Notes
Journal Article
Research Support, Non-U.S. Gov't
Résumé
In order to elucidate the geometric organization of projections from the barrel cortex to the thalamus, iontophoretic injections of the anterograde tracer Phaseolus vulgaris-leucoagglutinin were made. The injections were confined to one barrel column (i.e. barrel in layer IV + cortical tissue above and below it). Axonal terminations could be demonstrated in three thalamic nuclei: reticularis (RT), ventrobasalis (VB) and posterior (PO). Anterograde terminal labelling was obtained in RT + VB; in PO only; or in RT + VB + PO. The terminals labelled in PO were much larger than those in RT and VB. The termination areas in RT, VB and PO were shaped like rods which have a rostro-caudal orientation. These cortico-thalamic projections are discretely and topographically organized. The clearest such arrangement was found in VB. Here, projections from the A row of barrels in BF terminate dorsally, whereas those from the C row end ventrally. Barrel A1 projects to the lateral part of VB, whereas A4, to more medial parts; other rows are arranged similarly. These results were compared with the distribution of thalamo-cortical projection neurons that were labelled after iontophoretic HRP injections in individual barrels. We concluded that the corticothalamic projections originating from one barrel column contact an are of barreloids in VB.
Mots-clé
Animals Female Horseradish Peroxidase/diagnostic use Male Mice Mice, Inbred ICR Phytohemagglutinins/diagnostic use Somatosensory Cortex/*physiology *Synaptic Transmission Thalamus/*physiology Vibrissae/*physiology
Pubmed
Web of science
Création de la notice
24/01/2008 15:41
Dernière modification de la notice
20/08/2019 13:32
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