Evaluation of prenatal diagnosis of cleft lip with or without cleft palate and cleft palate by ultrasound: experience from 20 European registries. EUROSCAN study group.

Détails

ID Serval
serval:BIB_0A0E4F6650BB
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Titre
Evaluation of prenatal diagnosis of cleft lip with or without cleft palate and cleft palate by ultrasound: experience from 20 European registries. EUROSCAN study group.
Périodique
Prenatal Diagnosis
Auteur⸱e⸱s
Clementi M., Tenconi R., Bianchi F., Stoll C.
Collaborateur⸱rice⸱s
EUROSCAN study group
ISSN
0197-3851
Statut éditorial
Publié
Date de publication
2000
Peer-reviewed
Oui
Volume
20
Numéro
11
Pages
870-875
Langue
anglais
Notes
(Addor M.C. included in EUROSCAN study group)
Résumé
Ultrasound scans in the mid-trimester of pregnancy are now a routine part of antenatal care in most European countries. Using data from registries of congenital anomalies a study was undertaken in Europe. The objective of the study was to evaluate prenatal detection of cleft lip with or without cleft palate (CL(P)) and cleft palate (CP). All CL(P) and CPs suspected prenatally and identified at birth in the period 1996-98 were registered from 20 Congenital Malformation Registers from the following European countries: Austria, Croatia, Denmark, France, Germany, Italy, Lithuania, Spain, Switzerland, The Netherlands, UK, Ukraine. These registries followed the same methodology. A total of 709,027 births were covered; 7758 cases with congenital malformations were registered. Included in the study were 751 cases reported with facial clefts: 553 CL(P) and 198 CP. The prenatal diagnosis by transabdominal ultrasound of CL(P) was made in 65/366 cases with an isolated malformation, in 32/62 cases with chromosomal anomaly, in 30/89 cases with multiple malformations and in 21/36 syndromic cases. The prenatal diagnosis of CP was made in 13/198 cases. One hundred pregnancies were terminated (13%); in 97 of these the cleft was associated with other malformations.
Mots-clé
Cleft Lip, Cleft Palate, Europe, Gestational Age, Registries, Ultrasonography, Prenatal
Pubmed
Web of science
Création de la notice
02/04/2009 8:52
Dernière modification de la notice
20/08/2019 12:32
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