Early improvements in vision after fractionated stereotactic radiotherapy for primary optic nerve sheath meningioma

Détails

ID Serval
serval:BIB_09F022DD3BDB
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Titre
Early improvements in vision after fractionated stereotactic radiotherapy for primary optic nerve sheath meningioma
Périodique
Radiotherapy and Oncology
Auteur(s)
Baumert  B. G., Villa  S., Studer  G., Mirimanoff  R. O., Davis  J. B., Landau  K., Ducrey  N., Arruga  J., Lambin  P., Pica  A.
ISSN
0167-8140 (Print)
Statut éditorial
Publié
Date de publication
08/2004
Volume
72
Numéro
2
Pages
169-74
Notes
Journal Article --- Old month value: Aug
Résumé
BACKGROUND AND PURPOSE: To report on the efficacy and follow-up of 23 patients with primary optic nerve sheath meningioma (ONSM) with fractionated stereotactic conformal radiotherapy (SCRT). PATIENTS AND METHODS: Between 1996 and 2003, 23 patients ( = 23 eyes) with ONSM were treated. Indications for primary stereotactic radiotherapy were tumour progression documented by imaging or symptoms (loss of vision, pain). All patients received SCRT with a median dose of 50.4Gy in 6 weeks. RESULTS: After a median follow-up of 20 months (1-68 months) a 95% (21 of 22) visual control was seen: vision improved in 16 patients and remained stable in 5. For 13/16 patients improvement was documented already within 1-3 months after SCRT. Vision became worse in one patient. An improvement of pain was observed after radiotherapy in 6 patients as well as of proptosis in 1 patient. For 1 patient pain was persistent after SCRT. In one patient 4 years after SCRT a radiation retinitis and vitreous haemorrhage was seen. CONCLUSIONS: Fractionated stereotactic radiotherapy improves vision, often shortly after treatment, and is thus a viable treatment option for this tumour entity.
Mots-clé
Adolescent Adult Aged Child Dose Fractionation Female Follow-Up Studies Humans Male Meningeal Neoplasms/*radiotherapy Meningioma/*radiotherapy Middle Aged Nerve Sheath Neoplasms/*radiotherapy Optic Nerve Neoplasms/*radiotherapy *Radiotherapy, Conformal/methods Stereotaxic Techniques Time Factors Treatment Outcome Vision/*radiation effects Vision Tests
Pubmed
Web of science
Création de la notice
28/01/2008 13:43
Dernière modification de la notice
20/08/2019 13:32
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