Effect of angiotensin converting enzyme inhibition in renovascular hypertension.
Détails
ID Serval
serval:BIB_09A669FE1A27
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Synthèse (review): revue aussi complète que possible des connaissances sur un sujet, rédigée à partir de l'analyse exhaustive des travaux publiés.
Collection
Publications
Institution
Titre
Effect of angiotensin converting enzyme inhibition in renovascular hypertension.
Périodique
Journal of Hypertension. Supplement
ISSN
0952-1178
Statut éditorial
Publié
Date de publication
1989
Volume
7
Numéro
7
Pages
S27-31
Langue
anglais
Notes
Publication types: Journal Article ; Review - Publication Status: ppublish
Résumé
The unique ability of angiotensin converting enzyme (ACE) inhibitors to inhibit the generation of angiotensin II has made them very useful agents for treating patients with renovascular hypertension. Their efficacy in lowering blood pressure in this type of secondary hypertension is now well established. However, episodes of acute renal failure may occur during ACE inhibition, particularly when renal perfusion is compromised. This is often the case in patients with renal artery stenosis and a single kidney or with bilateral renal artery stenosis. In recent years, investigators have shown concern at the long-term fate of the stenotic kidney in patients with unilateral renal artery stenosis who are treated with ACE inhibitors. Although overall renal function remained stable, a decrease in glomerular filtration was demonstrated in the stenotic kidney under ACE inhibition. The long-term implications of this observation merit further investigations.
Mots-clé
Angiotensin II, Angiotensin-Converting Enzyme Inhibitors, Glomerular Filtration Rate, Humans, Hypertension, Renovascular, Kidney Failure, Acute, Renal Artery Obstruction, Time Factors
Pubmed
Web of science
Création de la notice
05/03/2008 17:39
Dernière modification de la notice
20/08/2019 13:31