Effects of growth hormone administration in addition to gonadotrophins in normally ovulating women and polycystic ovary syndrome (PCO) patients.

Détails

ID Serval
serval:BIB_097270F98B9F
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Effects of growth hormone administration in addition to gonadotrophins in normally ovulating women and polycystic ovary syndrome (PCO) patients.
Périodique
Human Reproduction
Auteur⸱e⸱s
Volpe A., Artini P.G., Barreca A., Minuto F., Coukos G., Genazzani A.R.
ISSN
0268-1161 (Print)
ISSN-L
0268-1161
Statut éditorial
Publié
Date de publication
1992
Volume
7
Numéro
10
Pages
1347-1352
Langue
anglais
Notes
Publication types: Journal ArticlePublication Status: ppublish
Résumé
Follicular fluid sex-steroids, insulin-like growth factor-I (IGF-I), IGF-I binding protein (IGF-I-BP) and epidermal growth factor were investigated in patients with polycystic ovaries and normally ovulating women, following ovulation induction with gonadotrophins or growth hormone plus gonadotrophins. Growth hormone supplementation enhanced the ovarian response to gonadotrophins, and significantly increased follicular fluid IGF-I in both groups, without affecting follicular fluid epidermal growth factor; growth hormone supplementation significantly decreased follicular fluid androstenedione in both groups.
Mots-clé
Adult, Androstenedione/biosynthesis, Carrier Proteins/biosynthesis, Drug Synergism, Epidermal Growth Factor/biosynthesis, Estradiol/biosynthesis, Female, Follicular Fluid/chemistry, Follicular Fluid/drug effects, Gonadotropins/pharmacology, Growth Hormone/pharmacology, Humans, Infertility, Female/drug therapy, Insulin-Like Growth Factor Binding Protein 1, Insulin-Like Growth Factor I/biosynthesis, Ovulation/drug effects, Ovulation Induction/methods, Polycystic Ovary Syndrome/drug therapy, Progesterone/biosynthesis
Pubmed
Web of science
Création de la notice
14/10/2014 11:43
Dernière modification de la notice
20/08/2019 12:31
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