High prevalence of hypovitaminosis D in a Swiss rheumatology outpatient population.

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Etat: Public
Version: de l'auteur
ID Serval
serval:BIB_07E57C46D35E
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Titre
High prevalence of hypovitaminosis D in a Swiss rheumatology outpatient population.
Périodique
Swiss Medical Weekly
Auteur(s)
Stoll D., Dudler J., Lamy O., Hans D., So A., Krieg M.A., Aubry-Rozier B.
ISSN
1424-3997 (Electronic)
ISSN-L
0036-7672
Statut éditorial
Publié
Date de publication
2011
Volume
141
Numéro
w13196
Pages
1-5
Langue
anglais
Résumé
Vitamin D is important for bone metabolism and neuromuscular function. While a routine dosage is often proposed in osteoporotic patients, it is not so evident in rheumatology outpatients where it has been shown that the prevalence of hypovitaminosis D is high. The aim of the current study was to systematically evaluate the vitamin D status in our outpatient rheumatology population to define the severity of the problem according to rheumatologic diseases. During November 2009, all patients were offered a screening test for 25-OH vitamin D levels and categorised as deficient (<10 µg/l [ng/ml] [25 nmol/l]), insufficient (10 µg/l to 30 µg/l [25 to 75 nmol/l]) or normal (>30 µg/l [75 nmol/l]). A total of 272 patients were included. The mean 25-OH vitamin D level was 21 µg/l (range 1.5 to 45.9). A total of 20 patients had vitamin D deficiency, 215 patients had an insufficiency and 37 patients had normal results. In the group of patients with osteoporosis mean level of 25-OH vitamin D was 25 µg/l and 31% had normal results. In patients with inflammatory rheumatic diseases (N = 219), the mean level of 25-OH vitamin D was 20.5 µg/l, and only 12% had normal 25-OH vitamin D levels. In the small group of patients with degenerative disease (N = 33), the mean level of 25-OH vitamin D was 21.8 µg/l, and 21% had normal results. Insufficiency and deficiency were even seen in 38% of the patients who were taking supplements. These results confirm that hypovitaminosis D is highly prevalent in an outpatient population of rheumatology patients, affecting 86% of subjects. Despite oral supplementation (taken in 38% of our population), only a quarter of those on oral supplementation attained normal values of 25-OH vitamin D.
Pubmed
Web of science
Open Access
Oui
Création de la notice
14/06/2011 13:52
Dernière modification de la notice
20/08/2019 13:30
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