Indications et résultats du traitement des neurinomes de l'acoustique par radiothérapie stéréotaxique avec LINAC: résultats préliminaires [Indications and results of stereotactic radiosurgery with LINAC for the treatment of acoustic neuromas: preliminary results]

Détails

ID Serval
serval:BIB_05B937AE251B
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Titre
Indications et résultats du traitement des neurinomes de l'acoustique par radiothérapie stéréotaxique avec LINAC: résultats préliminaires [Indications and results of stereotactic radiosurgery with LINAC for the treatment of acoustic neuromas: preliminary results]
Périodique
Annales d'Oto-Laryngologie et de Chirurgie Cervico Faciale
Auteur(s)
Radu A., Pica A., Villemure J.G., Maire R.
ISSN
0003-438X
Statut éditorial
Publié
Date de publication
07/2007
Volume
124
Numéro
3
Pages
110-114
Langue
français
Notes
English Abstract Journal Article --- Old month value: Jul
Résumé
INTRODUCTION: Radiosurgery is presently becoming an alternative to microsurgical resection of acoustic neuromas. The interest of radiosurgery consists in its lower morbidity compared to surgery and likely in similar rates of long-term tumor control. The goal of our study was to assess the clinical outcome (hearing preservation and neurological complications) as well as tumor control after low-dose radiosurgery for unilateral acoustic neuromas. MATERIAL AND METHODS: Since April 2002, 22 patients with untreated acoustic neuromas underwent stereotactic radiosurgery using a linear accelerator (LINAC) and a micromultileaf collimator (mMLC, Brain Lab) at a low-dose of 12 Gy. The average age was 56.4 years (range 29-73 years). The treatment volume was 0.03 to 6.04 cm(3) (median 1.85 cm(3)). The median follow-up period was 18 months (range 6-36 months). RESULTS: No morbidity was observed during the treatment. Preservation of a serviceable hearing (classes I and II according to the Gardner-Robertson scale) was achieved in 10 of 14 patients (71%). Radiological tumor growth control was obtained in all patients (100%). Trigeminal neuropathy was observed in two patients. One of these patients also experienced a slight facial weakness. CONCLUSIONS: Low dose radiosurgery provides a low rate of post-therapeutic morbidity and yields the preservation of a serviceable hearing in 70% of cases. Tumor control is observed in all patients, but a longer follow-up period is needed to confirm the stability of the tumor size.
Mots-clé
Adult, Aged, Equipment Design, Female, Humans, Magnetic Resonance Imaging, Male, Middle Aged, Neoplasm Staging, Neuroma, Acoustic/pathology, Neuroma, Acoustic/surgery, Radiosurgery/instrumentation, Treatment Outcome
Pubmed
Création de la notice
25/01/2008 11:00
Dernière modification de la notice
20/08/2019 12:27
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