Effects of 12-h sleep deprivation and of 12-h cold exposure on sleep regulation and cortical temperature in the rat.

Détails

ID Serval
serval:BIB_052B1BEB6DE1
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Effects of 12-h sleep deprivation and of 12-h cold exposure on sleep regulation and cortical temperature in the rat.
Périodique
Physiology & behavior
Auteur⸱e⸱s
Franken P., Tobler I., Borbély A.A.
ISSN
0031-9384
Statut éditorial
Publié
Date de publication
11/1993
Peer-reviewed
Oui
Volume
54
Numéro
5
Pages
885-894
Langue
anglais
Résumé
The predictions of the two-process model of sleep regulation were tested by 12-h sleep deprivation (SDEP) and 12-h cold exposure (cold, 4 degrees C) in the rat, both carried out in the 12-h dark period. The analysis was based on recordings of vigilance states, electroencephalogram (EEG) power spectra (0.25-25.0 Hz), and cortical temperature (Tcrt). During recovery from SDEP, slow-wave activity (SWA; EEG power density in the 0.75-4.0 Hz band) in non-REM sleep was higher and the number of brief awakenings (nBA) lower than in the corresponding baseline period. During recovery from cold, a moderate and delayed increase in SWA was present. During SDEP, Tcrt was above baseline, and in some intervals of recovery below baseline. In those intervals waking was also decreased. During recovery from cold, Tcrt and waking were not affected. It is concluded that 12-h SDEP causes an intensification of sleep, as indicated by the enhanced SWA and the reduced nBA, whereas 12-h cold has only marginal effects. The time course of SWA in both experiments could be accurately predicted by a computer simulation based on the assumption of the two-process model and the parameter values determined in a previous experiment.
Mots-clé
Animals, Arousal/physiology, Body Temperature Regulation/physiology, Cerebral Cortex/physiology, Cold Temperature, Computer Simulation, Electroencephalography/instrumentation, Energy Metabolism/physiology, Male, Rats, Rats, Sprague-Dawley, Signal Processing, Computer-Assisted/instrumentation, Sleep Deprivation/physiology, Sleep Stages/physiology, Sleep, REM/physiology, Wakefulness/physiology
Pubmed
Web of science
Création de la notice
24/01/2008 16:31
Dernière modification de la notice
20/08/2019 13:26
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