Did Dumbo suffer a heart attack? independent association between earlobe crease and cardiovascular disease.

Détails

Ressource 1Télécharger: BIB_04DCD1862D8E.P001.pdf (491.38 [Ko])
Etat: Public
Version: de l'auteur
ID Serval
serval:BIB_04DCD1862D8E
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Titre
Did Dumbo suffer a heart attack? independent association between earlobe crease and cardiovascular disease.
Périodique
Bmc Cardiovascular Disorders
Auteur(s)
Aligisakis M., Marques-Vidal P., Guessous I., Vollenweider P.
ISSN
1471-2261 (Electronic)
ISSN-L
1471-2261
Statut éditorial
Publié
Date de publication
2016
Peer-reviewed
Oui
Volume
16
Numéro
1
Pages
17
Langue
anglais
Notes
Publication Status: epublish
Résumé
BACKGROUND: Earlobe crease (ELC) has been associated with cardiovascular diseases (CVD) or risk factors (CVRF) and could be a marker predisposing to CVD. However, most studies studied only a small number of CVRF and no complete assessment of the associations between ELC and CVRF has been performed in a single study.
METHODS: Population-based study (n = 4635, 46.7 % men) conducted between 2009 and 2012 in Lausanne, Switzerland.
RESULTS: Eight hundred six participants (17.4 %) had an ELC. Presence of ELC was associated with male gender and older age. After adjusting for age and gender (and medication whenever necessary), presence of ELC was significantly (p < 0.05) associated with higher levels of body mass index (BMI) [adjusted mean ± standard error: 27.0 ± 0.2 vs. 26.02 ± 0.07 kg/m(2)], triglycerides [1.40 ± 0.03 vs. 1.36 ± 0.01 mmol/L] and insulin [8.8 ± 0.2 vs. 8.3 ± 0.1 μIU/mL]; lower levels of HDL cholesterol [1.61 ± 0.02 vs. 1.64 ± 0.01 mmol/L]; higher frequency of abdominal obesity [odds ratio and (95 % confidence interval) 1.20 (1.02; 1.42)]; hypertension [1.41 (1.18; 1.67)]; diabetes [1.43 (1.15; 1.79)]; high HOMA-IR [1.19 (1.00; 1.42)]; metabolic syndrome [1.28 (1.08; 1.51)] and history of CVD [1.55 (1.21; 1.98)]. No associations were found between ELC and estimated cardiovascular risk, inflammatory or liver markers. After further adjustment on BMI, only the associations between ELC and hypertension [1.30 (1.08; 1.56)] and history of CVD [1.47 (1.14; 1.89)] remained significant. For history of CVD, further adjustment on diabetes, hypertension, total cholesterol and smoking led to similar results [1.36 (1.05; 1.77)].
CONCLUSION: In this community-based sample ELC was significantly and independently associated with hypertension and history of CVD.
Pubmed
Web of science
Open Access
Oui
Création de la notice
29/01/2016 15:40
Dernière modification de la notice
20/08/2019 13:26
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