Assessing Pseudomonas aeruginosa Persister/antibiotic tolerant cells.

Détails

ID Serval
serval:BIB_03FD913C231C
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Synthèse (review): revue aussi complète que possible des connaissances sur un sujet, rédigée à partir de l'analyse exhaustive des travaux publiés.
Collection
Publications
Titre
Assessing Pseudomonas aeruginosa Persister/antibiotic tolerant cells.
Périodique
Methods in Molecular Biology
Auteur(s)
Hazan R., Maura D., Que Y.A., Rahme L.G.
ISSN
1940-6029 (Electronic)
ISSN-L
1064-3745
Statut éditorial
Publié
Date de publication
2014
Peer-reviewed
Oui
Volume
1149
Pages
699-707
Langue
anglais
Notes
Publication types: Journal Article ; Research Support, N.I.H., Extramural Publication Status: ppublish
Résumé
Bacterial persistence, which is observed in a broad range of microbial species, is the capacity of a bacterial cell subpopulation called "persisters" to tolerate exposure to normally lethal concentrations of bactericidal antibiotics. This ability, which is not due to antibiotic-resistant mutants, has been implicated in antibiotic treatment failures and may account for latent, chronic, and relapsing infections. Antibiotic tolerant/Persister (AT/P) cells have been notoriously difficult to study due to their low frequency and transient nature. This chapter describes the main methods used to isolate and study Pseudomonas aeruginosa AT/P cells and discusses new technologies that may ease research of P. aeruginosa persisters in the near future.
Pubmed
Web of science
Création de la notice
28/10/2014 10:08
Dernière modification de la notice
20/08/2019 13:25
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